Pilot Plant Downstream Processing Operator

Manus works across industries and value chains to accelerate the transition to Bio Alternatives - better performing and more sustainable versions of complex molecules traditionally sourced from plants, animals, or fossil fuels. Our platform is proven to work across scales, bridging the Valley of Death between lab and manufacturing more efficiently and more reliably to deliver the benefits of synthetic biology today.

We are seeking a highly motivated Pilot Plant Downstream Processing Operator. This person will be expected to play an integral part of Manus’ manufacturing and process development team located in Augusta, GA.

The Pilot Plant Downstream Processing Operator is responsible for the continuing efficient operation of the pilot plant. This includes maintenance, equipment reliability, and operations. Creativity and decision-making skills are required. Must be able to maintain a good working relationship with all personnel. Work as a member of the pilot plant team which includes assisting both with fermentation and downstream work assignments.

Controls, monitors, and measures processes as instructed. Abides by all safely, environmental, and quality requirements. Perform minor maintenance and duties related to product testing, including sampling.

• Opportunity – For motivated, results-oriented team members, our growth creates opportunities for personal and professional advancement.
• Accountability – You are given the resources you need to succeed and the freedom to make it happen; in return, we hold each other accountable for our high expectations.
• Passion – We love what we do and enjoy working with others who feel the same way. We embrace the challenge and hard work that come with working on the cutting edge.

Interface with process development team to provide resources to solve fermentation and product isolation challenges. Execute and help evaluate experiments. This activity includes:

• Perform downstream purification operations including centrifugation, chromatography (e.g., affinity, ion exchange), filtration (TFF, depth, sterile).
• Set up, operate, and clean process equipment such as columns, tanks, and filtration systems.
• Collect, label, and process in-process and final product samples.
• Monitor process parameters, record data, and ensure batch documentation is completed accurately.
• Perform cleaning and sterilization of equipment and cleanroom areas (CIP/SIP procedures).
• Assist in deviation investigations and continuous improvement initiatives.
• Collaborate with upstream and quality departments to ensure efficient process flow and product quality.
• Maintain inventory of DSP consumables and request resupply as needed.
• Become familiar with all required batch records, execute according to the batch records and ensure clear communication of the targeted design parameters.
• Execute day-to-day Pilot Plant activities, coordinating equipment maintenance and installation activities, troubleshooting process upsets, troubleshooting equipment and instrumentation problems, optimizing operations, addressing contamination issues, addressing downtime or other runtime losses.
• Maintain the upkeep of the Pilot Plant equipment through the process of initiating work notifications/work orders and maintenance scheduling;
  Be capable of correcting minor maintenance issues.
• Adhere to company environmental, safety, and health policies and procedure. Ensure Pilot Plant compliance with safety and environmental regulations.
• Physical demand requirements are more than sedentary work due to inspection of equipment. Must be able to climb stairs and ladders. Must be able to lift 50 pounds.

This position involves work on the third floor of the facility and requires occasional manual handling of hazardous materials, including carrying pitchers of sulfuric acid and glassware (such as beakers, flasks, and similar lab equipment).

• The role also involves working around hot steam tanks, requiring strict adherence to safety procedures and use of appropriate personal protective equipment (PPE) at all times.
• At certain times, the employee may be required to work alone, necessitating…