Scientist, In Vivo Immunology

At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people by the end of the decade. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease.

We believe the Greater Boston area is an important hub for the biotech and pharma industry, which is why we’ve invested in growing our footprint and expanding our R&D space in Cambridge, building a new hub for vaccine discovery.

The Scientist in the In Vivo Immunology team will support preclinical in‑vivo studies and will represent the project team in spearheading GSK’s innovation of novel viral vaccines and platform programs. You will help design and write in vivo study protocols, coordinate and initiate preclinical studies, conduct experiments, and analyze experimental data on cellular mediated and humoral immune responses of novel vaccine candidates, formulations, and platforms.

• Act as the preclinical in‑vivo study point of contact in a matrix team to support identification of novel vaccine candidates and platform development.
• Design, plan, conduct, coordinate, monitor, and analyze in‑vivo studies for vaccine and platform programs.
• Schedule, manage, and track the life cycle of in‑vivo studies.
• Conduct dosing, perform IVIS imaging, and collect tissues; be trained and experienced in animal handling, sample collection, and surgical procedures.
• Ensure adherence to GSK and regulatory requirements for compliance with IACUC guidelines by writing and reviewing in‑vivo study protocols.
• Perform complex flow cytometry, particularly for characterizing immune responses in preclinical immunogenicity or challenge studies.
• Develop new flow cytometry panels and troubleshoot experiments.
• Analyze experimental data and document them in detail using an electronic notebook.
• Prepare and document study protocols and final study reports as an author.
• Contribute to technical sections of patent applications, IND submissions, and scientific publications.
• Present study plans and results at project meetings.
• Develop new experimental techniques based on project needs.

• Ph.D., M.S., or B.S. degree in immunology or a related field. Required post‑graduate work experience: 0 years for Ph.D., 4+ years for M.S., 8+ years for B.S.
• Experience conducting in‑vivo animal studies within vaccines, infectious diseases, or immunology.

• Ph.D. with experience in viral immunology or infectious disease.
• Experience with in‑vivo viral challenge models.
• Experience working with multiple species.
• Strong experience with immune‑response readout methods such as ELISA, flow cytometry, Luminex, or qPCR methodologies.
• Deep understanding of immunology.
• Worked in a matrix team.
• A collaborative team player with strong interpersonal skills to work with various groups within the organization.
• Detail‑oriented with the agility to balance multiple projects with short timelines.
• Experience in documentation of study protocols and reports.
• Excellent communication and writing skills.

Salary for this position ranges from $89,925 to $149,875 annually for eligible locations, and includes an annual bonus and eligibility to participate in GSK’s share‑based long‑term incentive program. Benefits include health care and other insurance, retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.