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Principal Scientist - Biophysics

Job in Chapel-en-le-Frith, High Peak, Derbyshire, SK22, England, UK
Listing for: Concept Life Sciences Group
Full Time position
Listed on 2026-05-21
Job specializations:
  • Science
    Research Scientist
  • Research/Development
    Research Scientist
Salary/Wage Range or Industry Benchmark: 125000 - 150000 GBP Yearly GBP 125000.00 150000.00 YEAR
Job Description & How to Apply Below
Location: Chapel-en-le-Frith

Job Role: Principal Scientist - Biophysics
Site: Chapel-en-le-Frith
Contract:12- month FTC
Salary: Competitive – DOE

Concept Life Sciences seeks an experienced Biophysicist to be a part of our integrated team of Protein Science, Biophysics and Structural Biology. A subject matter expert, you will apply deep expertise across Biophysical standalone and matrix Drug Discovery projects to guide client programmes, deliver high quality data and insights, and contribute to the continued growth and technical excellence of the department.

What

you will be doing:

This senior role is based within our multi-disciplinary department of Protein Science, Biophysics and Structural Biology (PBSB), reporting to the department Director. The successful candidate will provide scientific leadership to Drug Discovery projects, interpreting complex Biophysical data sets and pragmatically recommending how our clients may advance their research programmes.

Whilst this is primarily a lab-based role, and dependent on experience, you will also drive activities associated with promoting the growth, efficiency and scientific advancement of the PBSB department. In addition, you may develop junior colleagues through training and mentoring.

The role is Biophysics focussed (SPR, GCI, ITC, DLS, ELS, DSF, DLS, DSC, NTA, SEC-MALS) and complimentary skills in Protein Production are highly desirable. Experience in Structural Biology may also be considered.

As a Project Leader, you will take the lead on Biophysics Drug Discovery projects from initial client interaction through to successful project delivery, working closely with Business Development colleagues in this client facing role. There will be a high degree of input into Business Development, including generating technical proposals and relevant marketing material.

The successful candidate will have significant interaction with external clients and a range of internal stakeholders including scientific peers, Business Development and Marketing to ensure the scientific excellence and integrity of services delivered.

As a company that operates globally, travel may be required. This role may also require occasional travel to our Edinburgh site (project dependent).

About you:
  • Deep subject matter expertise (wide range of Biophysical techniques required) gained in a CRO (preferred), Academic, Biotech, or Pharma environment.
  • Significant experience applying a broad range of Biophysical techniques in a Drug Discovery environment.
  • Experience in Protein Science highly desirable.
  • Experience in other Structural Biology techniques (e.g. X-ray crystallography, Cryo-EM, Protein NMR) preferred.
  • Successful track record leading scientific projects in a client‑facing role.
  • Has supported development of more junior colleagues.
  • Liaison with and management of external vendor relationships.
  • Relevant PhD or equivalent postgraduate experience to demonstrate deep subject matter expertise.
What you will get:

In addition to a competitive salary, we provide generous holiday entitlement, a pension scheme with enhanced employer contributions, a health cash plan covering a range of therapy treatments, a cycle to work scheme, a retail discount scheme, death in service benefit, a discretionary bonus scheme, and free on-site parking.

You’ll also have access to our BHN Extras platform, offering cashback, discounts, and tech/home purchases via salary sacrifice.

Colleague wellbeing is important to us, we offer 24/7 virtual GP access, emotional support services, and a comprehensive wellbeing hub. We’re proud of our inclusive, supportive culture and provide a range of learning and development opportunities to help you grow both personally and professionally.

About Concept Life Sciences:

Concept Life Sciences is a multi-disciplined Contract Research Organisation based in the UK providing market-leading scientific services globally. Over the past 25 years, Concept Life Sciences and its heritage companies have played a pivotal role in guiding numerous clients along their path to clinical success and many of these clients have evolved into enduring scientific collaborators.

From our 4 sites across the UK, we provide world-leading expertise to the pharmaceutical, biotech, agrochemical, and material science industries. We have clients across Europe, Asia, and the US, who value our knowledge-based, science-led, and customer-focused approach.

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