Genomics AI Program Manager

The Genomics AI Program Manager will support a Center-wide Initiative at the New York Genome Center (NYGC) focused on advancing the development and application of artificial intelligence and machine learning approaches to genomic interpretation and human disease. The Initiative brings together NYGC faculty, technologists, computational scientists, and external collaborators to develop and apply large-scale AI models that link genomic sequence to cell-type–specific regulation, disease phenotypes, and biological function.

The mission of the Genomics AI Initiative is to address key bottlenecks in genomic interpretation by integrating high-throughput sequencing, single-cell and spatial multiomics, perturbation and functional genomics, and modern machine learning approaches. This effort is inherently interdisciplinary and collaborative, requiring close coordination across scientific domains, data production and infrastructure, and external collaborative partners.

The Program Manager will provide coordination and operational leadership across the full range of activities undertaken by the Genomics AI Initiative. This includes day-to-day management of complex, multi-investigator scientific collaborations; coordination of Consortium-wide activities such as working groups, journal clubs, and symposia; development of scientific and programmatic materials; and support for grant and philanthropic proposal development.

The Program Manager will play a central role in enabling collaboration across NYGC leadership, faculty, Genomics AI fellows, external collaborators, and commercial partners by tracking scientific progress, facilitating data access and sharing, supporting computational infrastructure planning, and ensuring alignment across teams. This position will report to the Scientific Director & CEO, or an individual designated by the Scientific Director & CEO, and will work closely with the Genomics AI Initiative participants.

This role sits at the intersection of genomics, data science, and program coordination and is well-suited for an incumbent adept at working across scientific disciplines and operational functions.

Genomics AI Program Management

• Manage and coordinate the scientific projects and collaborative activities of the Genomics AI Initiative in alignment with the goals and timelines;

• Support Genomics AI Initiative leadership in organizing and running working groups, steering committee meetings, journal clubs, workshops, and symposia;

• Track scientific objectives, milestones, action items, and dependencies across participating labs and teams, and regularly communicate progress to the Genomics AI Initiative leadership;

• Coordinate the development, review, and dissemination of relevant materials, including presentations, reports, white papers, and scientific summaries;

• Support development of grant applications, philanthropic proposals, and progress reports in collaboration with faculty, Research Administration, and Development;

• Facilitate communication across Genomics AI Initiative participants to ensure alignment, transparency, and efficient collaboration; and

• Organize meetings, prepare agendas and briefing materials, record meeting notes, and track follow-up actions.

Data, Infrastructure, and Computational Coordination

• Coordinate data sharing, access, and staging across NYGC teams and external collaborators, in partnership with Informatics, IT, and Data Engineering groups;

• Work with NYGC’s compliance officers and DARB to ensure that data usage is compliant and maintain a list of approved datasets as they relate to AI model development;

• Serve as a liaison between scientific teams and operational groups to support troubleshooting related to data availability, compute usage, workflows, and analysis pipelines; and

• Track dataset access and usage, benchmarking activities, and model development milestones across projects.

Genomics AI Initiative Operations and Engagement

• Support onboarding and coordination of Genomics AI Fellows and participating researchers;

• Support development of inter-institutional workflows and agreements, including data access and use, collaboration, etc.;

• Develop and manage annual budgets for Genomics AI Initiative activities and related grant proposals, and monitor expenditures throughout the year to ensure fiscal responsibility and alignment with program priorities;

• Assist with planning and execution of scientific events and external engagement activities;

• Help maintain strong working relationships among NYGC faculty, fellows, staff, and external partners; and

• Contribute to long-term planning for the growth, sustainability, and evaluation of Genomics AI Initiative.

Please note that this job description is not designed to cover or contain a comprehensive listing of activities, duties, or responsibilities required of the employee for this job. Duties, responsibilities, and activities may change.

• Advanced degree (PhD, MS, or equivalent) in genomics,…