Senior Manager, Medical Information, CardioMetabolic

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs. With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees.

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive.

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

The Senior Manager, Medical Information will report to the Associate Director, Medical Information and be an important component of the team s individual will provide integral support to the cross functional Cardio Metabolic team by executing Medical Information activities in alignment with strategy and direction established by the Core Medical Team. This position is responsible for the provision of accurate, timely, and relevant medical information in response to inquiries from healthcare providers, healthcare organizations, patients, and caregivers for the Cardio Metabolic Therapeutic Area.

This position will also support congress booth activities, and other Medical Information initiatives. The candidate will have a clinical, scientific, and pharmaceutical industry background as well as understanding of Medical Information principles, guidelines, and industry standards. This role may be based either on‑site or remotely with occasional work expected from our Carlsbad, CA or Boston, MA offices, as well as travel to support medical congresses.

• Create, proactively update, and facilitate the review of Medical Information content (standard response letters, custom responses, and FAQs) in alignment with established Medical Information strategy, policies and standards.
• Collaborate with call center staff to handle inquiries for the assigned Therapeutic Area, ensuring responses are timely, accurate, fair-balanced, evidence-based and in alignment with applicable guidelines, regulations, and company policies.
• Manage call center inquiry escalations by conducting scientific assessments, developing appropriate responses, and coordinating review as appropriate.
• Develop and maintain an in‑depth understanding of product knowledge in the assigned Therapeutic Area, labeling, associated disease states, relevant scientific and medical literature, treatment guidelines, and competitive landscape.
• Critically evaluate literature, interpret complex data, write effectively, and clearly communicate recommendations.
• Provide Medical Information support at medical congresses including staffing the Medical Information Booth and supporting congress planning activities.
• Provide support to the Associate Director for other critical Medical Information projects including tactical execution of initiatives, content development, and operational activities as needed.
• Demonstrate strong independent judgment and ownership within…