Senior Scientist, Cell Therapy TRC In Vivo Pharmacology

Position Summary

The In Vivo Pharmacology team in the Cell Therapy Thematic Research Center has an opening for a highly collaborative and creative Sr. Scientist with a dedication to discovery and development of novel engineered immune effector cell therapeutics for the treatment of cancer and other chronic diseases. The successful candidate will have a strong scientific track‑record demonstrating their expertise in immuno‑oncology, particularly related to tumor and immune response models in mice, and a desire to lead functional work streams from early stages/target concept through to IND filing.

The role will encompass the direct supervision and mentorship of research associates and contribute to scientific and strategic leadership for the pharmacology function in the context of collaborative, cross‑functional BMS R&D project teams. This position is ideal for a motivated and interactive scientist who is passionate about cell therapy and has a proven track record working across highly matrixed teams to drive key decisions for drug discovery and development.

• Lead functional work streams on highly matrixed cell therapy research project teams from target concept to IND.
• Represent the in vivo pharmacology function on cross‑functional research teams, effectively influencing scientific decisions, building alignment, and communicating clear scientific recommendations.
• Independently design, execute, and interpret complex in vivo pharmacology studies supporting engineered immune cell therapy programs, ensuring next logical steps based on experimental results.
• Independently author high‑quality scientific documents, including presentations, study reports, protocols, and publications; contribute to regulatory and IP filings.
• Present complex concepts to a range of audiences including governance and departmental meetings.
• Integrate literature, emerging technologies, and evolving immunotherapy modalities to enhance study design and support the development of novel engineered immune cell therapeutics.
• Supervise and mentor colleagues through functional guidance, scientific feedback, and day‑to‑day technical support, fostering strong technical execution and scientific rigor.
• Excel in a fast‑paced team environment, meet deadlines, and prioritize work on multiple projects while fostering open and productive scientific communication and collaboration.

• Bachelor’s Degree – 7+ years of academic and/or industry experience.
• Master’s Degree – 5+ years of academic and/or industry experience.
• Ph.D. or equivalent advanced degree in Life Sciences – 2+ years of academic and/or industry experience.

• Ph.D. in Immunology, Cancer Biology, Virology or related field with demonstrated expertise in in vivo immuno‑oncology models and immune effector cell biology.
• 4+ years of post‑degree experience in industry settings focused on immune‑based therapies, in vivo immunology, or engineered cell therapies.
• Advanced proficiency in murine tumor model development—including syngeneic, xenograft, and/or T‑cell driven models—with a track record of designing and executing studies that inform mechanistic understanding and therapeutic advancement including: cell‑based therapies, immunotherapies, and drug combination studies.
• Familiarity with gene editing technologies and delivery methods (e.g., adeno‑associated viral vectors, non‑viral delivery, CRISPR gene editing).
• Proven capability to influence project direction through clear communication, scientific leadership, and representation of the in vivo pharmacology function in cross‑functional settings.
• Strong record of scientific authorship, including internal reports, external publications, and contributions to patents or regulatory documentation.

Seattle - WA: $136,030 - $164,841. The starting compensation range(s) for this role are listed above for a full‑time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule,…