Scientist, Thymus- Therapeutics

Position: Scientist, Thymus-Based Therapeutics
The Job Details are as follows:
California, US residents  ((12-22-23) %20

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Who We Are
We are the first publicly‑traded biotech or pharmaceutical company to take the form of a public benefit corporation. Our public benefit purpose is to provide a brighter future for patients through the development of novel pharmaceutical therapies; and technologies that expand the availability of transplantable organs. United Therapeutics (Nasdaq:  UTHR ) seeks to travel down the corridors of indifference to develop treatments for rare, deadly diseases.

We were founded in 1996 by a family seeking a cure for their daughter’s pulmonary arterial hypertension ( PAH ). Today, we have six FDA‑approved therapies that treat PAH, pulmonary hypertension associated with interstitial lung disease ( PH-ILD ) and neuroblastoma, a rare pediatric cancer. Our near‑term pipeline seeks to develop additional therapies for PAH and pulmonary fibrosis ( PF ).

Who You Are
Do you want to be involved at the start of a brand‑new program and contribute to scientific advancements? The Scientist, Thymus‑based Therapeutics (Preclinical & Translational Research) is responsible for performing preclinical and translational research, contributing to the establishment of a new research group and laboratory facility, and making direct contributions to the preclinical development pipeline through the advancement of in vitro and in vivo immunology platforms.

Independently plan, execute, and analyze experiments in human thymus and T cell biology, including human primary cell culture, cell isolation assays, and in vitro T cell functional assays

Perform multi‑parameter flow cytometry and analysis

Perform immunofluorescence tissue staining, imaging, and quantitative analysis

Contribute to the planning, execution, and data analysis of humanized mouse models for preclinical evaluation

Set up and help manage new lab spaces, including equipment organization, workflow development, and establishment of standard operating procedures

Coordinate effectively with external vendors, animal care facilities, and Contract Research Organizations (CROs) to support in vivo studies and data generation

Maintain detailed experimental records, analyze complex datasets, and present findings to the team

Actively contribute to building a collaborative, high‑performing research group in a dynamic startup culture

Minimum Requirements

2+ years of relevant postdoctoral or industry experience with a Doctor in Philosophy (PhD) in immunology, biomedical sciences, experimental medicine, or a closely related field

Strong hands‑on experience with human primary cell culture and sterile techniques

Proficiency in flow cytometry (panel design, acquisition, and data analysis)

Experience with cell isolation assays from human samples

Hands‑on experience with immunofluorescence tissue staining, imaging, and analysis

Proven ability to work independently with minimal supervision, including designing, planning, executing, and troubleshooting experiments

Excellent experimental planning and strong time management skills to deliver on project timelines

Strong team player with excellent communication and collaboration skills

Highly organized, detail‑oriented, and proactive

Learning and contributing to preclinical models and translational research

Enthusiasm for working in a fast‑paced, startup‑like environment and helping establish a new research laboratory and team

Preferred Qualifications

Experience planning and analyzing data from humanized mouse models

Direct experience working with thymus and T cell platforms

Job Location
This role is located 100% onsite in Vancouver, British Columbia.

United Therapeutics is an equal opportunity employer committed to diversity and inclusion.

Accommodations for persons with disabilities required during the recruitment process are available upon request.

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