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Senior Scientist
Job in
Waltham, Middlesex County, Massachusetts, 02451, USA
Listed on 2026-06-05
Listing for:
Berg Health
Full Time
position Listed on 2026-06-05
Job specializations:
-
Research/Development
Research Scientist -
Healthcare
Job Description & How to Apply Below
POSITION SUMMARY:
We are seeking a highly motivated Senior Scientist, Proteomics to join our Translational Research team and play a central role in advancing a novel therapeutic asset across rare mitochondrial disorders, neurological diseases, oncology, and other indications. This individual will be a key driver of mechanism-of-action (MoA) studies, biomarker discovery/validation, enabling data-driven decision-making across preclinical and clinical development.
ESSENTIAL DUTIES AND RESPONSIBILITIES:
- Design and execute discovery and targeted proteomics experiments to support MoA, pharmacodynamics, and biomarker identification.
- Lead analysis of complex biological samples (plasma, tissue, CSF, cellular systems) using LC-MS/MS-based proteomics platforms.
- Drive biomarker discovery and validation, translating proteomic findings into clinically relevant biomarker candidates.
- Collaborate closely with biology, pharmacology, bioinformatics, and clinical teams to support translational research strategy.
- Interpret and present results to cross-functional teams, and external collaborators.
- Contribute to regulatory and publication-quality documentation, including study reports and manuscripts.
- Stay current with advances in proteomics technologies, computational tools, and analytical methods to continuously improve platform capabilities.
- Other duties, as assigned.
- Ph.D. in Proteomics, Biochemistry, Molecular Biology, Analytical Chemistry, or a related field.
- 4+ years of industry experience in proteomics or translational biomarker research (biotech or pharmaceutical environment preferred).
- Strong hands-on expertise in mass spectrometry-based proteomics
- Ability to work with an interdisciplinary team of biologists, chemists, and computational scientists to deeply characterize and understand the proteomes of cells, biofluids, and tissues.
- Demonstrated ability to analyze, interpret and present data in a clear fashion.
- Experience integrating proteomics with multi-omics datasets and systems biology approaches is desired
- Solid scientific training/productivity as identified through high-impact publications demonstrating creative thinking as well as innovative technical approaches.
Position Requirements
10+ Years
work experience
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