Postdoc - Innovative Biopredictive Dissolution

How can experimental dissolution science and digital approaches help us better understand the performance of tomorrow’s oral medicines? We are seeking a curious and motivated Postdoc to join our Biopharmaceutics and Dissolution Sciences team in Biberach. You will lead a research project focused on advancing biopredictive dissolution approaches for challenging compounds and advanced oral formulations.

Combining hands-on laboratory research, mechanistic interpretation and modern digital tools, you will explore how drug substance properties, formulation attributes and experimental conditions influence in vitro performance and support oral formulation development.

Working with multidisciplinary experts and state-of-the-art technologies, you will build your independent research profile and gain experience in pharmaceutical development, with opportunities for peer-reviewed publications and international scientific exchange.

This position is part time eligible with 80 %.

Postdoc:
This Position is limited for 2 years.

Note:

To make it easier to find our job advertisements, we use the usual designation  postdoc . Of course, this advertisement is not only addressed to applicants directly after completing their doctorate, but to all qualified candidates.

• You independently design, conduct and evaluate studies to develop physiologically relevant, biopredictive dissolution approaches for challenging compounds and advanced oral formulations.
• By investigating dissolution, supersaturation and precipitation, you derive mechanistic insights into how drug substance properties, formulation attributes, manufacturing variables and test conditions influence in vitro performance.
• Building on these insights, you apply the developed approaches to drug development questions and critically assess their applicability and limitations.
• Your findings enable you to develop practical recommendations and best practices for oral drug product development.
• Using digital, data-driven and computational tools, you analyze complex datasets and support evidence-based decisions.
• As part of a multidisciplinary environment, you collaborate with experts in formulation development, biopharmaceutics, pharmacokinetics, modeling and regulatory sciences.
• Through scientific reports, peer-reviewed publications and presentations, you communicate your research findings to internal teams and at international conferences.

• PhD in Pharmacy, Pharmaceutical Sciences, Chemistry, Food Science or a related discipline.
• Hands-on experience in dissolution testing, oral formulation development, biopharmaceutics or a related experimental field. Experience with poorly soluble compounds, amorphous solid dispersions, supersaturation or precipitation is advantageous.
• Experience in analytical method development using techniques such as HPLC/UPLC, UV spectroscopy or comparable methods. Experience with solid-state or particle characterization, imaging or laboratory automation is advantageous.
• Sound understanding of oral drug absorption and its relationship to drug substance properties, formulation performance and gastrointestinal conditions. Knowledge of physiologically relevant dissolution testing, IVIVR/IVIVC, PBBM/PBPK modeling or regulatory biopharmaceutics is advantageous.
• Ability to independently plan and conduct experiments, critically analyze complex datasets and draw clear scientific conclusions. Interest or experience in computational tools, scientific informatics, knowledge management or AI-enabled knowledge discovery is desirable. Experience with statistical data analysis is advantageous.
• Scientific curiosity, a proactive and well-organized working style, and the ability to collaborate across disciplines and…