Senior Scientist Recombinase Optimization, Wuppertal

At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our capabilities and redefining ‘impossible’. There are so many reasons to join us.

If you’re hungry to build a varied and meaningful career in a community of brilliant and diverse minds to make a real difference, there’s only one choice.

You want to combine scientific excellence with hands‑on bench work and actively shape the optimization of site‑specific recombinases for eukaryotic systems? In this role, you co‑lead a cross‑division project between Crop Science Plant Biotech and Pharma R&D Genomic Medicine and build high‑performing assay and screening platforms to enable recombinase optimization.

• Co‑lead and support the optimization of site‑specific recombinases for use in eukaryotic systems as part of a joint project between Crop Science Plant Biotech and Pharma R&D Genomic Medicine
• Collaborate closely with Plant Biotech colleagues to advance recombinase applications across multiple biotechnology areas
• Develop, implement, and run mammalian cell‑based high‑throughput assays and screening cascades for recombinase activity
• Design and execute optimization and protein engineering strategies to improve site‑specific recombinases
• Perform molecular biology work related to protein engineering (e.g., library cloning and NGS‑based analysis)
• Execute established high‑throughput assays for recombinase activity in bacterial systems
• Potentially design and perform in‑vitro biochemical/biophysical assays to characterize recombinase activity
• Evaluate data, prepare reports/presentations, and support cross‑functional alignment and go/no‑go decisions

• PhD in biochemistry, molecular biology, biotechnology, or a related field, with a strong passion for hands‑on lab work
• Strong first‑hand experience and deep understanding of modern genome editing methods;
  Previous industry experience is a plus
• Direct experience with site‑specific recombinases is a plus
• Solid experience with state‑of‑the‑art mammalian cell culture, ideally in high‑throughput screening cascades
• Familiarity with protein engineering (e.g., structure–activity relationships, library generation methods, modern AI/ML‑based methods)
• Familiarity with modern NGS workflows and Python‑based NGS analysis tools
• Excellent teamwork and communication skills, high learning agility, strong self‑organization, and willingness to take project responsibility
• Fluent in English, written and spoken, with strong communication and presentation skills

• We ensure your financial stability with a competitive salary between 86.075€ and 93.800€ per year (full‑time) plus a variable component. Your compensation is based on your qualifications, skills, and professional experience.
• Whether it’s hybrid work models or part‑time arrangements:
  Whenever it is possible, you will have the flexibility to work how, when and where it is best for you.
• Your family is a top priority. We offer loving company daycare centers at multiple locations, support in finding childcare, time off for the care of elderly or dependent family members, summer camps for children, and much more
• We support your professional growth by providing access to learning and development opportunities, training programs through the Bayer Learning Academy, development dialogues,…