Portfolio Leader; Cross Portfolio + Strategy & Operations

Position: Portfolio Leader (Cross Portfolio + Strategy & Operations)
The Position

At Roche/Genentech, we have a bold Pharma Ambition to deliver 20 transformative medicines addressing diseases with the highest societal burden by 2030. With this vision top of mind, our purpose is to co-create and deliver the target portfolio for the benefit of patients. We want you to join our vision and be part of our passionate, collaborative, global PSM community!

We are a strong, close, trusting community that lives new ways of working and operates from a creative mindset. We are THE place for talent to grow and contribute; our talent feels valued, connected, and a sense of belonging to something impactful. We have high impact; customers draw on our expertise to help them deliver the target portfolio more effectively/efficiently. We stop lower-value work.

We’re BOLD. We try things, openly discuss and learn from mistakes and failure, experiment and iterate to achieve our aspirations.

The Opportunity

As Portfolio Leader(Cross Portfolio + Strategy & Operations), you will serve as a strategic partner and operational leader at the heart of our mission to actively shape and deliver a transformative Pharma portfolio. You will partner with the Head of PSM to drive the strategy, business planning, operations, and team culture, ensuring our PSM team is aligned, agile, and positioned for impact in a complex and evolving landscape.

Your responsibilities will also include leading and contributing to cross-portfolio initiatives, partnering with senior Pharma leaders and cross-functional teams to shape portfolio strategy, assess portfolio dynamics, and develop insights and strategic options to inform portfolio-wide decisions and prioritization. The balance between PSM-focused strategy and operations and broader portfolio-focused work may shift over time based on business needs.

Accountabilities include, but are not limited to, the following areas:

• Strategic Partner: Partner with the Head of PSM and the PSM Leadership Team to realize the strategic vision for PSM, and translating vision into actionable priorities. Partner with fellow LT members to co-create and implement PSM-wide initiatives.
• PSM Ecosystem Architecture and Functioning: Serve as the primary architect and steward of the PSM ecosystem, ensuring that culture, communications, and operational frameworks are seamlessly integrated to drive collective success. Lead the planning and facilitation of PSM LT and All Staff meetings, leveraging agile practices to enable rigorous discussion, clear decision‑making, and actionable outcomes. Oversee the holistic health of the PSM ecosystem by monitoring the intersection of team performance and organizational health, proactively identifying opportunities to strengthen the ecosystem.
• PSM Talent Deployment Architect and Decision Support: Build and manage systems and processes to match team skills and interests to the highest impact business needs, in support of PSM priorities.
• Operations Leadership and Culture Building: Operationalize strategic priorities while championing a connected team culture of learning, adaptability, operational excellence, and fun within the team.
• Liaison & Network Integrator: Represent PSM on Product Development work streams as needed. Take the lead on maintaining a strong Portfolio network with peer groups in gRED, pRED, and GPS.
• Cross-Portfolio Strategy and Special Projects: Partner with senior Pharma leaders and teams to shape portfolio-wide strategy and lead cross-portfolio initiatives and special projects. Structure complex, ambiguous questions, define the work and analysis needed, synthesize evidence and stakeholder perspectives into clear recommendations, and align contributors on plans and milestones to deliver agreed outcomes.
• Portfolio Assessments and Insights: As…