Scientist II, Fermentation Process Development – Recombinant Peptides

Scientist II, Fermentation Process Development – Recombinant Peptides

• Full-time
• Salary Min: 84500
• Salary Max: 162000
• Workday Global Grade: 16
• Compensation: USD 84,500 - USD 162,000 - yearly

About Abb Vie

Abb Vie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about Abb Vie, please visit us at  .

Follow @abbvie on Linked In, Facebook , Instagram , X and You Tube.

Abb Vie’s Biologics CMC organization develops processes to support the advancement and manufacture of biologic medicines. Abb Vie is seeking a motivated fermentation scientist to contribute to the development of microbial processes for recombinant peptide production. The successful candidate will perform hands‑on fermentation studies and help develop, optimize, and scale upstream processes for therapeutic peptides. This role will collaborate with colleagues in strain development, downstream processing, analytical development, and other functions to generate reliable data and support project goals.

Responsibilities

• Independently design, execute, and interpret critical fermentation experiments to answer scientific questions and advance project goals.
• Develop and optimize microbial cultivation and fermentation processes, including work with hosts such as Escherichia coli and yeast.
• Evaluate the effects of media composition, inoculum conditions, feed strategies, induction conditions, temperature, pH, agitation, aeration, and dissolved oxygen on growth and product expression.
• Operate, maintain, and optimize bench‑scale bioreactors and support microscale, parallel, and scale‑down fermentation studies.
• Apply broad technical proficiency to troubleshoot experiments, instrumentation, and routine process issues; adapt or innovate protocols and techniques as project needs evolve.
• Collaborate with strain‑development colleagues to screen and characterize microbial clones and expression systems.
• Analyze fermentation data—including growth, substrate use, process parameters, product titer, and yield—and place findings in the relevant scientific context.
• Troubleshoot experiments and instrumentation, adapting or developing methods to meet changing project needs.
• Collaborate with strain‑development, downstream‑processing, and analytical teams to assess expression, peptide recovery, and product quality.
• Consult relevant scientific literature and use it to inform experimental design, interpret findings, and solve technical problems.
• Set and meet experimental timelines, communicate plans and results, contribute to technical documentation, and improve laboratory methods and operations.
• Follow applicable corporate standards for conduct, safety, material handling, and GxP compliance, as relevant to the work.

Master’s degree or equivalent with 5+ years of relevant experience or Bachelor’s degree or equivalent with 7+ years of relevant experience, is required.

Qualifications

• Theoretical and practical knowledge of microbial cultivation and fermentation, preferably using
  
  E. coli and/or yeast.
• Demonstrated ability to independently design, execute, and interpret critical experiments to answer scientific questions.
• Demonstrated ability to develop, adapt, and optimize experimental methods and techniques in response to project needs.
• Experience operating bioreactors and applying fermentation parameters such as pH, temperature, agitation, aeration, and dissolved oxygen.
• Ability to troubleshoot experiments and instrumentation, recognize significant…