Medical Affairs Manager

Location: Turbigo

Overview
We are seeking a Medical Affairs Manager (MAM) to join our Medical Affairs International TTR and Italy team, a group dedicated to upholding the highest standards of scientific integrity and fostering unbiased, balanced medical-scientific dialogue with the medical community. In this strategically important role, you will serve as a medical-scientific expert responsible for driving and supporting the Medical Affairs objectives for Alnylam’s designated therapeutic areas.

Working in close partnership with both local cross-functional teams and International and Global Medical Affairs, you will help ensure alignment in achieving country-level objectives while maintaining a strong focus on patient-centred, evidence-based medical practice. You will collaborate with colleagues across Medical Affairs, Clinical Research, Regulatory Affairs, Value and Access, R&D, Patient Advocacy, Commercial and other key functions—always operating within the highest ethical, legal, regulatory, and industry standards.

This role offers the opportunity to shape scientific engagement, strengthen evidence generation and dissemination, and build trusted relationships across the ATTR landscape. The position is hybrid and based in Milan, Italy.

Key Responsibilities

Support the development and implementation of the strategy and tactical plans for new product launches as well as all for marketed products in close collaboration with all internal stakeholders. This relates to:

Evidence generation

Evidence dissemination – including HCP education programs

Key thought leader engagement programs

Continuously develop the highest medical-scientific expertise within ATTR Neuropathy (PN) and Cardiomyopathy (CM) and be acknowledged externally and internally as an expert in these areas; by developing peer-to-peer scientific relationships with medical experts in particular and with HCPs in general and by providing medical-scientific support to cross-functional disease area teams.

Identify and cultivate a network of medical-scientific experts in the field of ATTR.

Identify (country specific) evidence gaps and develop the evidence generation plan (including Alnylam sponsored studies, collaborative research agreements and the assessment of investigator-initiated studies requests received from medical experts).

Develop and support the implementation of highest quality medical education activities, including congress symposia, hospital/health care professional educational meetings.

Provide medical-scientific input concerning the development of advisory board meetings and support their execution.

Collaborate with patient advocacy groups.

Manage requests for Alnylam product supply in off-label and compassionate use cases in accordance with local laws and Alnylam procedures.

Coordinate the timely and appropriate response to Medical Information inquiries, utilizing global medical information resources and in line with local regulatory requirements.

Support internal stakeholders in the Market Access process.

Provide training and education for internal team members in relevant therapy areas and product training.

Qualifications

Degree in medical/natural science (PhD, MD, Pharm

D or equivalent).

MD (Medical Doctor) and/or PhD and/or equally academic qualified healthcare professional is preferred.

Previous experience in the field of TTR amyloidosis (neurology and/or cardiology) strongly preferred.

Proven basic science and/or clinical background to enable engagement of Health Care Professionals in a scientifically meaningful exchange.

Good analytical skills as applied to medical, scientific and technical information and the ability to cut through scientific complexity.

Experience in clinical research, and investigator-sponsored trials.

Experience in medical education and KOL engagement programs.

Effective communication skills of evidence based scientific information.

Knowledge of aspects of drug development, GCP and local regulations.

Ability to work collaboratively and cross-functionally.

Management and planning skills as well as decision-making and accountability.

Confident and has the professional competence to win respect and gain credibility at all levels within and…