Advance Therapy Product Translational Scientist

The John Goldman Centre for Cellular Therapy based at Hammersmith Hospital is a HTA, JACIE and MHRA IMP/ATMP licensed facility that provides highly specialist clinical, technical and scientific services for Bone Marrow transplant patients.

Applications are invited from well-motivated and organised individuals who will be involved in all aspects of GMP clinical processing (including advanced ATMP protocols and cell culture), flow cytometry and other quality testing.

The Advanced Therapy Product Translational Scientist will additionally be the lead in service developments such as ATMP validations, introduction of new techniques into the laboratory, quality system development, training, data management, assisting new/on-going translational research, handling commercially approved ATMP for clinical application, assisting in Clinical trials approval and bringing new therapies into clinical practice.

Applicants must have HCPC registration, minimum of an MSC level qualification with practical experience of GMP ATP manufacture / development or handling. Applicants should have direct experience in this field or in a related area such as Blood Transfusion, Immunology or ATP development under GMP conditions. In order to meet the needs of a high-quality service, the post holder is expected to be flexible in their working arrangements and be able to demonstrate the ability to work consistently under pressure to the highest standards.

To work with the Clinical Trials Lead and JGCCT Director to ensure that the JGCCT is ready to successfully delivery Advanced Therapy Medicinal Products (ATMPs) and Advanced Therapy Medicinal Investigational Products (ATMIPs) both within clinical trial and clinical practice setting.

To engage with all relevant stakeholders (internal and external) such as ATMP manufacturer(s), Pharmacy Clinical Trials & ATMPs and NHS clinical and research staff, Novel Activity and other relevant committees as applicable within the context of ATMP/ATIMPs provision at the Trust.

To develop and maintain all necessary standard operating procedures, documents, labels and guidelines in relation to ATMPs in conjunction with Pharmacy Clinical Trials & ATMP staff.

Lead laboratory ATMP manufacture and testing ready for clinical use.

Help monitor the clinical trial activity and reimbursement charges for the JGCCT.

At Imperial College Healthcare you can achieve extraordinary things with extraordinary people, working with leading clinicians pushing boundaries in patient care.

Become part of a vibrant team living our values - expert, kind, collaborative and aspirational. You'll get an experience like no other and will fast forward your career.

Benefits include career development, flexible working and wellbeing, staff recognition scheme. Make use of optional benefits including Cycle to Work, car lease schemes, season ticket loan or membership options for onsite leisure facilities.

We are committed to equal opportunities and improving the working lives of our staff and will consider applications to work flexibly, part time or job share. Please talk to us at interview.

To work with the Clinical Trials Lead and JGCCT Director to ensure that the JGCCT is ready to successfully delivery Advanced Therapy Medicinal Products (ATMPs) and Advanced Therapy Medicinal Investigational Products (ATMIPs) both within clinical trial and clinical practice setting.

Refer to the Job Description for detailed duties and responsibilities.

• MSc in appropriate specialist subject
• Health and Care Professions Council registration or Equivlent
• Good Manufacturing Practice (GMP) training/course.
• Quality Management course.
• GCP Training

• Minimum 2 years' experience in Blood Transfusion Science, Immunology or ATMP development laboratory with GMP
• Experience working in Grade B clean room production environment
• Experience of HPC processing and HPC quality testing.
• Experience in liaising with multidisciplinary teams

• Proactive
• Good interpersonal and organisational skills

• Excellent verbal and written communication skills
• Good ability to organise and prioritise work
• Technical aptitude
• Ability to work independently as well as in a team

• Good general health /fitness to practice to enable to fulfil the requirements of the role

This post is subject to the Rehabilitation of Offenders Act (Exceptions Order) 1975 and as such it will be necessary for a submission for Disclosure to be made to the Disclosure and Barring Service (formerly known as CRB) to check for any previous criminal convictions.