Ph.D. student area of Microtechnical Engineering and Microfluidics Point-of-Care Dia

The University of Applied Sciences and Arts of Southern Switzerland (SUPSI) invites applications for a Ph.D Student in the area of Microtechnical Engineering and Microfluidics for Point-of-Care Diagnostic Devices , at the Institute of Digital Technologies for Personalised Healthcare (Me Di Tech ) within the Department of Innovative Technologies (DTI), located in Lugano.

The position is part of the international project SMILE – Saliva-based Microfluidic “Lab-on-Chip” device for Paediatric Respiratory Viral Illness diagnostics , funded by the Swiss National Science Foundation (SNSF) and carried out in collaboration with EPFL , Swiss TPH , and the Centre Suisse de Recherches Scientifiques (CSRS) in Côte d’Ivoire.

The degree of employment is 100%, with a contract starting on 01.02.2026, or on a mutually agreed date.

• Applied research activities in the design, modelling, and fabrication of integrated microfluidic devices for point-of-care diagnostics.
• Precision mechanical design of the device modules (pre-treatment and hybridization chambers, microfluidic channels and connectors) and of the mechanical interfaces with optical and bioimpedance sensors.
• Analysis and optimization of microfluidic flows (laminar regime, diffusion, mixing, volume and pressure control) through numerical simulation and experimental validation.
• Selection and characterization of hydrophilic and biocompatible materials (PDMS, polycarbonate, silica, resins) for microfabrication, including bonding and sealing techniques.
• Development and testing of fluidic actuation and control strategies (peristaltic, capillary or pressure-driven), in collaboration with the project partners.
• Contribution to the manufacturing and mechanical validation of prototypes and test benches, in synergy with EPFL (biosensors) and Swiss TPH (diagnostic validation).
• Preparation of technical documentation, project reports and scientific publications in English.

• Master’s degree in Mechanical Engineering, Microengineering, Mechatronics, Materials Science or related fields.
• Proven experience in precision mechanical design and CAD / CAE modelling (preferably Siemens NX, ANSYS or equivalent).
• Basic knowledge of microfluidic principles and microfabrication techniques (soft lithography, etching, molding, micromachining).
• Experimental experience with mechanical or microfluidic laboratory instrumentation (microscopy, syringe pumps, molds, flow chambers, measurement equipment).
• Familiarity with polymeric and glass materials , adhesion and sealing methods, and their compatibility with biological fluids.

• Ability to work effectively both independently and collaboratively in an interdisciplinary and international team, with a focus on practical experimentation and strong motivation for applied research.
• Projects writing and funds acquisition.
• Very good communication skills in spoken and written English.

• Proven expertise in the field of biomedical technologies and medical devices.
• Knowledge of data analysis in Python and / or Matlab.

• Fixed-term employment contract.
• Fully funded Ph.D. scholarship.
• International working environment.
• Attractive salary in line with Swiss standards.
• Covering the costs of participation in high-profile conferences, and workshops.
• Opportunities to develop professional and scientific skills.

In all its actions, SUPSI guarantees an inclusive study and working environment that is accessible and respectful of all differences, in order to offer a high-quality university education to all. More about diversity and inclusion.