Research Associate – In Vivo Biology

6‑month contract-to-hire role, with the potential to convert to full-time based on performance and business needs

Help invent the future of lipid metabolism-based therapies for cancer and beyond

Lime Therapeutics is a venture-backed biotech startup pioneering therapies that target lipid-metabolic pathways in cancer, metabolic, and neurodegenerative diseases. We are advancing novel therapeutic concepts toward IND-enabling studies and clinical development. We are seeking a highly motivated Research Associate – In Vivo Biology to join our growing biology team and advance our oncology drug development programs.

You will work closely with experienced scientists to execute preclinical studies, evaluate novel therapeutic candidates, and generate high-quality data that directly informs our drug development decisions. This hands‑on role is ideal for an early-career scientist who is passionate about experimental biology, eager to build new technical skills, and excited to make a meaningful contribution at an early‑stage biotech company.

Research Associate – In Vivo Biology

6‑month contract-to-hire role, with the potential to convert to full-time based on performance and business needs

Help invent the future of lipid metabolism-based therapies for cancer and beyond

Lime Therapeutics is a venture-backed biotech startup pioneering therapies that target lipid-metabolic pathways in cancer, metabolic, and neurodegenerative diseases. We are advancing novel therapeutic concepts toward IND-enabling studies and clinical development. We are seeking a highly motivated Research Associate – In Vivo Biology to join our growing biology team and advance our oncology drug development programs.

You will work closely with experienced scientists to execute preclinical studies, evaluate novel therapeutic candidates, and generate high-quality data that directly informs our drug development decisions. This hands‑on role is ideal for an early-career scientist who is passionate about experimental biology, eager to build new technical skills, and excited to make a meaningful contribution at an early‑stage biotech company.

• Preclinical Oncology Studies: Conduct pivotal studies in relevant cancer models to evaluate the efficacy and tolerability of novel therapeutic candidates.
• Animal Handling and Dosing: Perform routine mouse handling, restraint, and compound administration by oral gavage and intraperitoneal (IP), subcutaneous (SC), and intravenous (IV) injection.
• Tissue Collection and Processing: Collect and process tissues for downstream molecular, biochemical, histological, and flow cytometry-based analyses.
• In Vitro Biology: Establish and maintain mammalian cell cultures, including cancer cell lines, primary cells, and organoids, and support cell-based assays and molecular biology experiments.
• Data Integrity and Analysis: Keep accurate experimental records, analyze study data in Graph Pad Prism and Excel, and clearly communicate results to the scientific team.
• Operational Excellence: Prepare experimental materials, maintain lab equipment and supplies, and ensure compliance with IACUC-approved protocols and lab safety standards.
• Collaboration and Flexibility: Work collaboratively in a fast‑paced startup, adapt to evolving research priorities, and support time‑sensitive experiments, including occasional evening or weekend work as animal study schedules require.

• Education and Experience: BS or MS in Biology or a related field, with hands‑on rodent in vivo experience and exposure to molecular assays in an academic, biotech, pharmaceutical, or CRO setting.
• In Vivo
  
  Skills:
  
  Demonstrated proficiency in mouse handling, restraint, and dosing, with working knowledge of IACUC protocols and animal welfare…