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Chemoinformatician; Principal Scientist​/Associate Director

Remote / Online - Candidates ideally in
England, UK
Listing for: One Nucleus Limited
Remote/Work from Home position
Listed on 2025-12-16
Job specializations:
  • Research/Development
    Research Scientist, Drug Discovery, Biotechnology, Data Scientist
Job Description & How to Apply Below
Position: Chemoinformatician (Principal Scientist / Associate Director)

OMass Therapeutics is a biotechnology company based in Oxford discovering medicines against highly‑validated target ecosystems, such as membrane proteins or intracellular complexes. The company’s unique Odyss

ION™ technology platform comprises novel biochemistry techniques, next‑generation native mass spectrometry, and custom chemistry. OMass is advancing a pipeline of small molecule therapeutics in rare diseases and immunological conditions, that target solute carriers, complex‑bound proteins, and GPCRs.

We are seeking an experienced Chemoinformatician. You will be part of a dynamic and innovative environment and will become an integral part of our vision to address patients’ unmet needs while building Britain’s Biggest Biotech. You will use your computational chemistry expertise and scientific curiosity to solve drug discovery challenges, as part of multi‑disciplinary project teams. You will be able to work in state‑of‑the‑art laboratory and modern facilities for optimum collaboration alongside a focused and caring team.

You will already possess expert Computational Chemistry knowledge with experience across all stages of a small‑molecule drug discovery from hit  to candidate nomination. The role is based in our Oxford site; however we are currently working a hybrid model with the option to work from home for part of the week.

To find out more about the meaningful work OMass delivers, as well as our EVP you can find this here.

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Position Requirements
10+ Years work experience
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