Bioinformatician​/Data Scientist

Company Description

Neo Phore is a biotech company targeting the dynamics of cancer neoantigen evolution through inhibition of the DNA mismatch repair (“MMR”) pathway, by changing the genotype of the tumour, to discover effective, well-tolerated medicines that will provide the next generation of cancer immunotherapies. Neo Phore collaborates closely with many academic and commercial organisations, including Neo Phore’s scientific founders Professor Alberto Bardelli and Dr Giovanni Germano at the University of Turin and Milan.

Neo Phore currently has 15 full-time employees and operates a primarily virtual drug discovery & development model. We have a dedicated internal Cancer Cell Biology (CCB) laboratory based at City St George’s University, in South London, where most of the innovative Biology associated with the progression of a first-in-class molecule is being performed. As the work outputs from novel investigative translational studies have successfully intensified and continues to progress and develop at pace, an opportunity has arisen for a bioinformatician or data scientist to join our team and support the bioinformatics function.

Neo Phore is seeking a bioinformatician or data scientist with knowledge in genomics, and NGS data analyses to support the bioinformatic function in the team. The successful candidate will mainly work alongside Neo Phore's Lead Computational Biologist, to provide accurate and timely-efficient analyses on experimental data to help extract biological insights on the key efficacy readouts following pharmacological inhibition of the DNA MMR pathway.

Evidence for a flexible and cooperative approach to working in a dynamic, collaborative and multi-disciplinary team environment, together with strong team ethic, are also essential. Important aspects of this role are, the ability to work and communicate effectively with team members and internal stakeholders from a wide variety of backgrounds. The ideal candidate will possess a strong desire to work in a fast-moving small molecule-focused translational research environment and needs to be highly analytical, self-motivated and organised.

The position is remote with monthly visits to the team in Neo Phore’s CCB laboratory in London (UK).

• Contribute to the development of pipelines (WES or WGS) and analysis of NGS data, supporting the efforts to better understand key efficacy readouts following pharmacological inhibition of the DNA MMR pathway.
• Test different software modules (tools) for biomarkers such as TMB, COSMIC signatures, MSI and more, under the guidance of the Lead Computational Biologist.
• Support internal and external collaborations by preparing datasets, running analyses, contributing to project deliverables, and preparing presentations.
• Assess and summarise literature findings to identify technical solutions and support project progression.
• Work collaboratively within a matrix environment.

• Knowledge in bioinformatics, statistics, genomics, and oncology.
• Fluent in at least one programming language with preference in python, and bash/Linux.
• Master’s or PhD in bioinformatics, computational biology, statistics, life sciences or related field.
• Be willing to work in a fast-moving small molecule-focused translational research environment and hold a record of successful delivery of scientific projects.
• Strong communication skills to work collaboratively within a matrix environment.
• Positive, passionate, with a can-do attitude.

The full-time position is home-based, with a 12-month fixed-term contract, and regular visits to the CCB laboratory facilities, based at City St George’s University, London, UK, and reporting to the Principal Scientist, Computational Biology. Compensation package to be agreed according to qualifications, including competitive salary.

Neophore Limited does not accept referrals from recruitment organisations for the vacancies posted on this site or those available in the public domain unless they have obtained prior written authorisation from the company. Any agreement between a recruitment agency and Neophore requires prior written consent. Without written authorisation, any actions taken by recruitment organisations will be considered unauthorised by Neophore Limited, and Neophore Limited will not be liable for any fees resulting from such actions or referrals.

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Neo Phore does not discriminate on the basis of race, sex, colour, religion, age, marital status, disability, veteran status, genetic information, sexual orientation, gender identity or any other reason prohibited by law in provision of employment opportunities and benefits.