Senior Biostatistician

Everest Clinical Research (“Everest”) is a full-service contract research organization (CRO) providing a broad range of expertise-based clinical research services to worldwide pharmaceutical, biotechnology, and medical device industries. We serve some of the best-known companies and work with many of the most advanced drugs, biologics, and medical devices in development today.

Everest has been an independent CRO since 2004 with a strong foundation as a statistical and data management center of excellence. Building on this foundation, Everest has successfully developed and established itself as a full-service CRO. Everest’s headquarters are located in Markham (Greater Toronto Area), Ontario, Canada with additional sites in Bridgewater (Greater New York City Area), New Jersey, USA, Shanghai (Pudong Zhangjiang New District), China and Taipei, Taiwan.

Everest is known in the industry for its high quality deliverables, superior customer service, and flexibility in meeting clients’ needs. A dynamic organization with an entrepreneurial origin, Everest continues to experience exceptional growth and great success.

Quality is our backbone, customer-focus is our tradition, flexibility is our strength…that’s us…that’s Everest.

To drive continued success in this exciting clinical research field, we are seeking committed, skilled, and customer-focused individuals to join our winning team as Senior Biostatisticians working remotely from a home-based office in the United Kingdom in accordance with our Work from Home policy.

Key Accountabilities :

1. Leadership and Project Management :

• Lead efforts in resolving day to day work related issues and problems, securing quality, improving efficiency and productivity of statistical and programming operations.
• Lead assigned projects by applying project management skills, statistical and programming techniques; achieve quality and on time delivery of deliverables, earn client’s trust and repeat business.

2. Statistical Planning and Methodologies :

• Provide statistical expertise for design, analysis and reporting of clinical trials and research projects.
• Contribute to the writing of statistical sections of study protocols, perform sample size calculation, develop randomization specifications, and generate randomization codes.
• Write Statistical Analysis Plans (SAPs) and properly address Peer Statistician review comments.
• Create and maintain Statistical and Programming Quality Control (QC) and QA Plans for assigned projects.
• Provide input to unblinded data management plan when required.
• Assist in research and development of statistical methodologies and processes.

3. Statistical Programming :

• Develop and / or review ADaM dataset specifications. Review and provide input to SDTM dataset specifications when required.
• Perform QC validation of analysis datasets and TLGs.
• Perform third level review of dry runs and final run.
• Lead statistical dry runs and final run by actively participating or contributing to project and resources management, addressing statistical and programming questions and interacting with data management to follow up and resolve data issues.
• Review and provide input to the Analysis Data Reviewer’s Guide, discuss and incorporate Data Standards Reviewer’s review comments to ensure quality of the document.

4. Statistical Analysis and Reporting, and Publication Support :

• Perform statistical analysis as per SAP, and address peer / QC review comments and findings.
• Perform statistical validation of core results, address additional QC validation comments and findings on the core results.
• Plan and conduct or contribute to the trial results reporting / dissemination meetings.
• Under supervision contribute to the contents describing any deviation from the planned analysis and deviation from study conduct for the Clinical Study Report (CSR). Review CSR to ensure accuracy, completeness and appropriateness of the interpretation of the statistical results.
• Write statistical report or statistical sections of the CSR.
• Perform statistical analyses for publications, including but not limited to abstracts, manuscripts, presentations and posters.

5. Supporting Clinical Data Collection and Cleaning :

• Prov…