Senior or Principal Scientist - In Vitro Pharmacology

Senior or Principal Scientist – In Vitro Pharmacology

We are looking for a Senior or Principal Scientist to join us in our In Vitro Pharmacology team, based in our Slough, UK facilities.

The primary role of this position is to drive the progression of immune cell engager antibodies from research towards clinical development. This is a laboratory‑based role focused on the design, optimisation, execution, and interpretation of high‑throughput cellular screening assays involving both cell lines and primary Human material from healthy donors and patients. These assays will be relevant for selecting & profiling novel immune cell engagers that target disease pathologies relevant to the patient value strategy of UCB.

You will report into a Senior Principal Scientist – In Vitro Pharmacology.

• Design, optimise, and perform pharmacologically relevant screening assays to investigate the function and mechanism of action of novel molecules and targets.
• Work safely within the laboratory environment by maintaining Health & Safety awareness.
• Use appropriate data analysis tools to interrogate, understand and display data.
• Maintain high‑quality records of experiments using appropriate digital platforms.
• Communicate experimental data at relevant forums; understand experimental findings and interpret appropriately for the wider team.
• Where appropriate, guide and mentor junior scientists, both planning and performing quality control of their work.

• Knowledge & experience related to T cell or immune cell engagement, in oncology or other disease areas.
• Experience developing in vitro assays to assess immune cell activation, cytotoxicity, and cytokine release.
• Experience with technologies and software packages including high‑throughput and high‑content platforms; automation and liquid handling, cytometry, imaging, immunoassays, and relevant molecular biology techniques.
• Experience working with primary Human cells and tissues, complying with HTA guidelines.
• Experience with large datasets from complex biological models, and associated skills in large dataset analytics.

Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

UCB is a global biopharmaceutical company, focusing on neurology and immunology. We are over 9,000 people in all four corners of the globe, inspired by patients and driven by science.

At UCB, we don’t just complete tasks, we create value. We aren’t afraid to push forward, collaborate, and innovate to make our mark for patients. We have a caring, supportive culture where everyone feels included, respected, and has equal opportunities to do their best work.

We ‘go beyond’ to create value for our patients, and always with a human focus, whether that’s on our patients, our employees, or our planet. Working for us, you will discover a place where you can grow, and have the freedom to carve your own career path to achieve your full potential.

At UCB, we’ve embraced a hybrid‑first approach to work, bringing teams together in local hubs to foster collaborative curiosity. Unless expressly stated in the description or precluded by the nature of the position, roles are hybrid with 40% of your time spent in the office.

UCB is an equal opportunity employer. All employment decisions will be made without regard to any characteristic protected by applicable laws.

Should you require any adjustments to our process to assist you in demonstrating your strengths and capabilities, contact us on EMEA-Rea Please note if your enquiry does not relate to adjustments we will not be able to support you through this channel.

• Mid‑Senior level

• Full‑time

• Research, Analyst, and Information Technology

• Pharmaceutical Manufacturing