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Senior Systems Biologist

Job in Mbombela, Mpumalanga, South Africa
Listing for: Placements24
Full Time position Listed on 2026-10-25
Job specializations:
  • Research/Development
    Research Scientist, Data Scientist, Biomedical Science, Biotechnology

Job Description & How to Apply Below

Location: Mbombela

About the Role

Our client, a forward-thinking biotechnology firm, is looking for a highly analytical and innovative Senior Systems Biologist to join their dynamic research team in Nelspruit
. This role is central to understanding complex biological systems through the integration of experimental data and computational modeling. The successful candidate will develop and apply multi-scale models to explore cellular processes, metabolic pathways, and gene regulatory networks. This position requires a strong foundation in quantitative biology and a passion for unraveling biological complexity. The role is based in Nelspruit, Mpumalanga, ZA
, and necessitates a full-time, on-site presence within their advanced research laboratories. We are seeking a dedicated scientist committed to advancing our understanding of biological systems.

Key Responsibilities
  • Develop and implement computational models of biological systems (e.g., metabolic networks, signaling pathways, gene regulation).
  • Integrate diverse experimental data types (genomics, proteomics, metabolomics) into systems biology frameworks.
  • Analyze large biological datasets to identify key mechanisms and predict system behavior.
  • Collaborate with experimental biologists to design hypothesis-driven experiments.
  • Validate model predictions through experimental results and refine models accordingly.
  • Utilize statistical and machine learning approaches for data analysis and model building.
  • Present research findings to both scientific and non-scientific audiences.
  • Contribute to the strategic direction of systems biology research within the company.
  • Mentor junior researchers and contribute to a collaborative research environment.
Requirements
  • Ph.D. in Systems Biology, Computational Biology, Biophysics, Biochemistry, or a related quantitative field.
  • Minimum of 7 years of experience in systems biology research, with a focus on modeling complex biological networks.
  • Strong background in quantitative analysis, mathematical modeling, and computational approaches.
  • Proficiency in programming languages such as Python, R, or MATLAB for data analysis and simulation.
  • Experience with relevant modeling software and biological databases.
  • Familiarity with high-throughput biological data types and analysis methods.
  • Excellent analytical and problem-solving abilities.
  • Strong communication and interpersonal skills, with the ability to work effectively in a multidisciplinary team.
  • Must be eligible to work in South Africa .
Benefits
  • A competitive annual salary of R .
  • Comprehensive medical and dental coverage.
  • Generous contribution to a retirement fund.
  • Opportunities for professional development, workshops, and conferences.
  • Access to state-of-the-art computational resources and laboratory facilities in Nelspruit .
  • A collaborative and intellectually stimulating work environment.
  • Annual performance-based bonus.

Position Requirements

10+ Years work experience
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