Director, Translational and Clinical Genetics

Company Overview

At GSK we have bold ambitions for patients aiming to positively impact the health of 2.5 billion people by the end of the decade. Our R&D focuses on discovering and delivering vaccines and medicines combining our understanding of the immune system with cutting‑edge technology to transform peoples fosters a culture ambitious for patients accountable for impact and committed to doing the right thing making sure that we focus our efforts on accelerating significant assets that meet patients needs and have the highest probability of success.

GSK has kicked off 2025 with impressive growth in sales profits and earnings. We anticipate five major new FDA product approvals and 15 phase III / pivotal study readouts over the next two years. So far we have secured two FDA approvals with three more expected later this year. By uniting science technology and talent we are committed to getting ahead of disease together.

We are seeking an innovative and motivated individual highly experienced in genetics and translational medicine to join the Translational & Clinical Genetics team which sits within the GSK Human Genetics and Genomics organisation. The successful candidate will conduct hands‑on data analyses and provide strategic leadership within cross‑functional scientific teams to identify develop and deliver novel programmes of work to impact the GSK pipeline.

You will have deep expertise in genetics and experience of integrating genetics with genomics (for example proteomics) and clinical phenotypes in data analyses. You will have the keen ability to understand the full context and nuances of a scientific question using your translational experience and link that detailed understanding to the design and delivery of customised analyses to efficiently address the specific question with expert interpretation and recommendations.

Your work will have application across therapeutic areas and across all stages of drug discovery and clinical development to inform target and biomarker discovery disease and mechanistic understanding indication and patient subgroup selection and treatment response optimisation using precision medicine approaches.

• Harness deep expertise in genetics with integration of genomic (genetic and proteomic) and clinical phenotypic data to undertake hands‑on innovative translational analyses to impact the GSK pipeline.
• Utilize your translational expertise and experience in close collaboration with GSK scientists and physicians from a range of functions to identify develop and deliver novel programs of data‑driven work to aid drug discovery and clinical development.
• Provide strategic leadership to cross‑functional GSK translational teams with an emphasis on project‑based work across GSK priority therapy areas.
• Identify, establish and oversee external scientific collaborations. These will primarily focus on new data generation access and analysis to catalyse translational insights relevant to GSK strategic priorities but may also include collaborations to deliver experimental medicine studies to further investigate data‑driven insights.
• Effective communication of analysis findings with expert interpretation and recommendations to project teams, and a broad range of stakeholders.
• Work with focus and agility to deliver objectives demonstrating strong statistical analytic and critical thinking skills with deep understanding of the translational context of your work.
• Stay informed about emerging technologies and methodologies in translational genetics and genomics.
• Foster a culture of innovation collaboration and continuous professional learning within the team.

• Medical degree
• PhD or equivalent advanced degree in a relevant scientific discipline (e.g. translational genetics, genetic epidemiology, biomedical statistics, computational sciences, bioinformatics or machine learning)
• Documented academic and/or clinical research publication history or history of medical practice in the fields noted above.
• Broad clinical knowledge across therapeutic areas and experience of clinical research to investigate translational questions.
• Hands‑on…