Postdoctoral Researcher

Join to apply for the Postdoctoral Researcher role at University Health Network

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care.

UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build a healthier world and it is only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

• Union:
  Non-Union
• Number of Vacancies: 1
• New or Replacement:
  New
• Site:
  Princess Margaret Cancer Centre
• Department:
  Princess Margaret Research Institute
• Reports to:
  
  Principal Investigator
• Salary Range: $55,000 – $65,000
• Hours:
  
  37.5 Per Week
• Shifts:
  
  Monday - Friday, Day Shifts
• Status:
  Temporary Full-time
• Closing Date:
  January 22, 2026

A POSTDOCTORAL RESEARCHER position is available in Toronto, Canada, in the laboratory of Aoki Lab at the Princess Margaret Cancer Centre, University Health Network; one of the top five cancer research centres in the world. The research focus is basic/translational research in cancer immunology and cancer genomic field in lymphoid malignancies. The successful applicant will analyze large scale cohort data in collaboration with world‑leading researchers and perform functional assays using state‑of‑the‑art preclinical models to develop novel treatments.

• Design and execute experiments to study the pathogenesis, molecular mechanism and treatment resistance mechanism, and tumour‑microenvironment interaction in lymphoid malignancies.
• Analyze and interpret molecular analyses from DNA/RNA sequencing data (including single‑cell sequencing, whole genome sequencing).
• Analyze and interpret spatial analyses (e.g., protein level and transcriptional level).
• Develop and oversee high‑throughput data pipelines, including data from many new single‑cell technologies such as scRNA‑seq, scATAC‑seq, sc Multiome‑seq, and Visium/Cos Mx spatial transcriptomics.
• Analyze sequencing data using established pipelines.
• Develop new computational methods to integrate and interpret multi‑omics data.
• Assist and collaborate with internal and external researchers in interpretation of sequencing data.
• Contribute to the codebase, development, and support of open‑source software packages.
• Help manage lab servers and computational infrastructure.
• Document and present results in written or oral reports to other lab members.
• Work collaboratively with other research team members and external collaborators.
• Participate in multidisciplinary projects combining biochemistry, structural biology, and computational methods.
• Stay updated with the latest research in cancer genomics, cancer immunology and lymphoma biology.
• Review and summarize relevant scientific literature to inform experimental design and data interpretation.
• Prepare manuscripts for publication in scientific journals.
• Present research findings at national and international conferences, seminars, and workshops.
• Assist in writing grant proposals to secure funding for ongoing and future research projects.
• Mentor and supervise graduate and undergraduate students involved in related research projects.
• Provide guidance on experimental techniques and data analysis.

• Ph.D. in bioinformatics, computer science or a recognised equivalent in Health and/or Science‑Related Discipline or a related field, obtained within the previous five years.
• Programming skills in R, Python, BASH, Tensor Flow or similar.
• Experience working in a Linux environment.
• Demonstrated exposure to NGS data analysis and…