Principal Scientist - In Vivo Pharmacology
Job in
Vancouver, BC, Canada
Listing for:
AbCellera
Full Time
position
Listed on 2025-12-31
Job specializations:
-
Research/Development
Research Scientist, Clinical Research
Salary/Wage Range or Industry Benchmark: 135000 - 168600 CAD Yearly
CAD
135000.00
168600.00
YEAR
Job Description & How to Apply Below
From target to the clinic. AbCellera’s platform integrates biology, computation, and engineering to develop impactful antibody-based medicines. We’re scientists, engineers, and business professionals who work together to turn scientific insights into breakthrough medicines. We pursue truth and scientific rigor. We think independently, act with conviction, and have the courage to work at the edge of the unknown. We offer the opportunity to stretch and explore, and to work on things that matter.
We are looking for a highly motivated Principal Scientist with a strong background in the preclinical development of biologics in an industry setting to join our team. You will contribute to the development and assessment of antibody-based drug candidates so that we can move programs faster and with less risk to the clinic. Your role will involve internal R&D as well as external collaborative research.
If you are someone who has a passion for understanding how models can predict therapeutic action in human disease, we want to hear from you!
How you might spend your days
Leading internal preclinical in vivo pharmacology studies to support programs around different disease indicationsDesigning, supporting execution, and interpreting in vivo pharmacology studies to generate proof-of-concept data and build confidence in selection of molecules for clinical developmentEvaluating available data sets to identify animal models, build testable biological hypotheses for new targets, and then preclinically assessing those hypothesesWork closely with the internal teams and/or external CROs, to effectively and efficiently execute in vivo preclinical studiesCollaborating with cross-functional project teams within protein engineering, in vitro biology, pharmacokinetics, modeling, and biomarkers to identify lead molecules and advance programs to human clinical trialsSupporting and mentoring in vivo pharmacology teammates by providing scientific expertise and practical support during preclinical study design, execution, and data analysisCollaborating with the project team and teammates on regulatory documents to support regulatory filingReporting findings to program teams and senior leadership to support data-driven decisionsWe'd love to hear from you if
You have a strong background in preclinical drug development of biologics in an industry setting, including discovery, identification and establishment of animal models, in vivo pharmacology, and efficacy in disease modelsYou have experience in oncology, immunology, or pain (desirable); scientific expertise in other disease areas will also be consideredYou have a PhD in pharmacology, immunology, or a related field, plus at least 8 years of experience in a biopharmaceutical industry setting; candidates with a MSc and 12+ years of relevant industry experience will also be consideredYou have proven interpersonal skills and create value on cross-functional teamsYou are genuinely curious, with an interest in discussing innovative ideas in a highly collaborative and fast paced environmentYou are good at communicating scientific and/or technical concepts with an emphasis on applicationYou are able to independently identify project needs and follow that up with constructing and implementing solutionsYou enjoy the teamwork that comes with working on complicated biological questions and building data sets that help to predict the success of therapiesWhat we offer
AbCellera’s hiring range for this role is CAD $135,000 - $168,600 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.
You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find we prioritize teams and social groups to build community and connections across AbCellera.
About Ab Cellera
AbCellera is a global company focused on delivering breakthrough medicines that alleviate suffering,…
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