Senior Software Engineer, Full Stack - Quantafold

About Us

Quantafold is a quantum-inspired drug discovery start-up headquartered in the UAE. We have developed a breakthrough physics-based engine to disrupt de novo protein target modelling. Our engine takes any protein structure and generates 1,000+ amino acid hit sequences against the target in minutes — replacing high-throughput screening entirely. Our ambition extends beyond a discovery service: we intend to build the UAE's first fully integrated pharmaceutical company, using service revenue to fund a proprietary pipeline and, eventually, GMP manufacturing in the UAE.

Quantafold is a quantum-inspired drug discovery start-up headquartered in the UAE. We have developed a breakthrough physics-based engine to disrupt de novo protein target modelling. Our engine takes any protein structure and generates 1,000+ amino acid hit sequences against the target in minutes — replacing high-throughput screening entirely. Our ambition extends beyond a discovery service: we intend to build the UAE's first fully integrated pharmaceutical company, using service revenue to fund a proprietary pipeline and, eventually, GMP manufacturing in the UAE.

This is a hands on founding engineer role who can operate in ambiguity, design real systems, build quickly, and guide others. The Senior Full Stack Engineer will be responsible for designing full stack architectures, developing pipelines, building reliable services, creating reusable foundations, and making sure MVPs are strong enough for real customer validation. The role requires deep software engineering experience across front end, back end, APIs, databases, cloud infrastructure, integrations, security, observability, and product delivery.

• Lead the technical design and development of pipelines, full stack products, MVPs, prototypes, internal tools, and customer-facing applications.
• Translate ambiguous business opportunities into technical architecture, delivery milestones, data models, API contracts, and implementation plans.
• Design and build front-end applications using modern frameworks such as React, Next.js, Type Script, or similar technologies.
• Design and build back-end services using technologies such as Node.js, Python, Java, or similar production-grade stacks.
• Define service boundaries, API contracts, database schemas, authentication flows, authorization models, and integration patterns.
• Build secure and scalable APIs using REST, GraphQL, OpenAPI, webhooks, event-driven patterns, and asynchronous processing where needed.
• Work with relational and non-relational databases such as PostgreSQL, MySQL, MongoDB, Redis, Elasticsearch, or vector-enabled stores.
• Design systems that include proper logging, tracing, metrics, audit trails, error handling, retry logic, rate limiting, and operational dashboards.
• Build applications that can integrate with internal platforms, third-party APIs, AI services, payment systems, identity providers, government systems, and enterprise systems.
• Own technical decisions around scalability, reliability, latency, data consistency, security, maintainability, and cost.
• Build reusable engineering foundations such as starter kits, shared components, service templates, deployment templates, API standards, and reference architectures.
• Partner with Staff AI Engineers to integrate AI capabilities into complete products, including RAG flows, agents, AI-powered workflows, document processing, and human review experiences.
• Guide engineers through architecture reviews, code reviews, test planning, production readiness, and incident learning.
• Help define engineering standards for CI/CD, automated testing, environment management, secrets management, release management, and cloud deployment.
• Support customer…