Manufacturing Associate

Arcinova
, A Quotient Sciences Company, is dedicated to providing innovative contract research, development, and manufacturing services. We offer a comprehensive range of integrated specialist services for early stage drug development, underpinned by strong industry knowledge and scientific expertise.

Our mission is to bring science, innovation, and collaboration together to overcome the barriers in drug development. We empower emerging biotechs and large pharma alike to bring life-changing therapies to patients faster, through an efficient, effective approach focused on quality, science, and innovation.

Our vision is to advance progress through science, delivering solutions that make a measurable difference. We look ahead with purpose, driven to shape a smarter, more resilient future for all.

This role is central to translating Arcinova’s mRNA manufacturing capability into a robust, repeatable, and client-ready service offering. By combining scientific understanding with disciplined GMP execution, the Manufacturing Scientist will help deliver high-quality mRNA drug substance and formulated bulk drug product for vaccine and therapeutic development programmes.

• Operate biofoundry-enabled, automated, modular, or continuous flow systems used for IVT, purification, formulation, and process intensification activities.
• Support process set-up, parameter verification, in-process sampling, process monitoring, and escalation of alarms, deviations, or unexpected trends.
• Contribute to the development of robust and repeatable workflows that support efficient transition from development-scale to GMP manufacture.
• Support technology transfer of client processes, internal platform processes, and new mRNA manufacturing workflows into the Arcinova manufacturing environment.
• Assist with process development, engineering runs, manufacturing readiness activities, material readiness, equipment readiness, and campaign planning.
• Provide practical manufacturing input into batch records, SOPs, risk assessments, process descriptions, sampling plans, and manufacturing instructions.
• Complete GMP documentation accurately, contemporaneously, and in accordance with data integrity expectations.
• Identify, report, and support investigation of deviations, non-conformances, process issues, and equipment events.
• Work in accordance with GMP, health and safety requirements, biosafety expectations, cleaning procedures, Grade C cleanroom gowning requirements, aseptic behaviors, and site quality systems.
• Work collaboratively with Analytical Development, Quality Assurance, Quality Control, Validation, and Supply Chain to deliver client projects.
• Support continuous improvement of mRNA manufacturing processes, documentation, equipment set-up, training materials, and operational ways of working.
• Maintain training compliance and contribute to a positive, safety-conscious, quality-focused manufacturing culture.
• Flex responsibilities, where required by business need, to support small molecule drug product manufacturing activities while maintaining appropriate training, GMP compliance, and quality standards.
• Operate, monitor and clean mRNA manufacturing equipment and single-use systems within a Grade C cleanroom, following approved procedures and batch records.
• Perform mRNA manufacturing activities, including in-vitro transcription, reaction monitoring, purification, concentration, buffer exchange and sterile filtration.
• Support mRNA formulation activities, including material preparation, controlled mixing, sampling, TFF and transfer to downstream operations.
• Operate automated, biofoundry-enabled and continuous flow manufacturing systems for IVT, purification and formulation processes.
• Support process setup, parameter checks, in-process sampling and performance monitoring, escalating issues where required.
• Contribute to developing robust, scalable workflows for GMP manufacturing.
• Support technology transfer of client, platform and new mRNA manufacturing processes into the Arcinova manufacturing environment.
• Assist with process development, engineering runs, manufacturing readiness and campaign planning activities.
• Contribute to batch…