Associate Scientist Cellular Immunology

Work with patient‑derived immune receptors to help discover personalised T cell therapies for cancer patients.

At AstraZeneca's Cell Therapy facility in Amsterdam, your work will directly contribute to developing the next generation of cancer treatments.

Associate Scientist Cellular Immunology

Amsterdam Zuid Oost (near Amsterdam UMC)

Fulltime – 40 hours per week

In this role, you will join our TCR Discovery team, where technologies are invented, developed and improved to identify and characterise patient‑specific T cell receptors for personalised cancer therapies.

You will work alongside around 75 scientists in an international, collaborative and dynamic environment at the forefront of cell therapy research.

As an Associate Scientist, you will spend most of your time in the lab working with patient‑derived samples and using techniques such as flow cytometry and viral transduction. This is a role in which you will do more than following established protocols: you will troubleshoot experiments, interpret results and contribute to improving the workflow.

This role is 95% lab‑based. Some experiments cannot be paused, so there may occasionally be times when you need to stay longer to complete an experiment. This role will suit someone who is naturally curious, enjoys solving experimental challenges, and likes to see experiments through from start to finish.

• Conducting TCR discovery and characterisation studies under the supervision of a senior Scientist.
• Isolating human immune cell populations including T cells, B cells and other subsets, using magnetic bead‑based methods.
• Assessing immune cells phenotypically and functionally using flow cytometry and microplate‑based assays.
• Genetically modifying primary immune cells and cell lines using retroviral and lentiviral vectors.
• Supporting the development and optimisation of assays.
• Documenting experimental results in the electronic lab journal and relevant databases.
• Keeping up to date with relevant scientific literature.
• Presenting results in internal work discussions.
• Contributing to day‑to‑day lab operations under the guidance of the Lab Manager.

Essential requirements:

This position is suitable for early‑career scientists who already have hands‑on experience working with mammalian cell culture in a research setting, gained through internships or employment.

To be considered for this position, you must meet all the requirements below:

• Bachelor's degree (HLO/BML equivalent), including at least two years of practical laboratory training, or a master’s degree in biomedical sciences or another relevant life science discipline.
• At least 12 months of hands‑on experience with mammalian or sterile cell culture, gained through research internships or employment. Experience gained solely in diagnostic laboratories does not meet this requirement.
• Practical knowledge of immunology gained through both education and laboratory work.
• Currently living within reasonable commuting distance of Amsterdam.
• Authorised to work in the Netherlands. Visa sponsorship is not available for this position.

Due to the specialised nature of this role, we are unable to consider candidates who do not meet the above‑mentioned criteria.

Because this role is intended for scientists with a bachelor’s or master’s level who are at an early stage in their research career, we are not considering applications from PhD graduates for this position.

• Enjoy solving experimental challenges, can distinguish priorities and are genuinely curious about understanding results.
• Are a team player with good social skills.
• Have a precise and detail‑oriented approach to laboratory work.
• Have strong written and verbal communication skills in English.

• An attractive bonus scheme and a 13th‑month salary on top of your monthly pay.
• Career growth opportunities, including international prospects.
• Access to internal training and development programs.
• 27 vacation days, plus additional leave (such as your birthday, Good Friday, and the period between Christmas and New Year’s Eve).
• Flexible and progressive employment…