Global Clinical Immunology Scientist

Job Title: Clinical Immunology Scientist
Location
:
Remote UK, South Africa Remote, US Remote, Amsterdam Remote,
Reporting to: Associate Director, Human Immunology, Human Immunology Lab

The Clinical Immunology Scientist supports the implementation and performance of immunological assays across IAVI-sponsored clinical trials and research programs. Working with Clinical Research Centers (CRCs), collaborating laboratories and Contract Research Organizations (CROs), the Scientist contributes to assay readiness, technology transfer, laboratory quality, training and data review activities that support reliable clinical trial data.

The Scientist provides remote and on-site technical support, identifies assay performance issues, recommends practical solutions within established study and laboratory plans, and escalates significant scientific or quality risks to senior scientific leadership and Quality Assurance, as appropriate.

The role supports preventive vaccine trials for emerging infectious diseases, including Lassa, Marburg and Ebola, as well as IAVI’s broader clinical trial and research portfolio. Working under general direction from senior scientific leadership, the Scientist applies advanced scientific and technical judgment to support assay implementation, performance monitoring, troubleshooting and data review.

• Provide scientific and technical support to CRCs, collaborating laboratories and CROs conducting immunological assays for IAVI clinical trials and research programs, with a particular focus on laboratories in Africa.
• Support defined assay lifecycle activities, including feasibility and laboratory readiness assessments, assay development and optimization, qualification and validation activities, technology transfer and implementation across collaborating laboratories.
• Provide remote and on-site technical support and training during assay transfer, implementation and performance monitoring.
• Apply hands‑on technical proficiency in immunological techniques, including ELISpot, ELISA, PBMC isolation and cryopreservation, neutralization assays, multiplex assays and flow cytometry.
• Review assay performance and laboratory data, identify technical or quality issues, support troubleshooting and root‑cause analysis, recommend corrective actions within defined procedures, and escalates issues requiring Quality Assurance or senior scientific leadership input.
• Support laboratory quality activities, by working within applicable GCP/GCLP requirements, study protocols, SOPs, laboratory quality systems and continuous-improvement activities.
• Support EQA program implementation, data analysis, reporting, troubleshooting and follow-up across participating laboratories.
• Contribute scientific and technical input to study and program teams on assay feasibility, laboratory performance, technical risks and clinical trial delivery requirements.
• Contribute technical observations and recommendations to support senior scientific decision‑making.

• Support laboratory operations required for clinical trial delivery, including equipment and reagent readiness, relevant documentation review, biosafety input, sample management and shipment coordination.

• Contribute to the review, analysis, interpretation and reporting of laboratory data in support of clinical trials and research programs, working with program personnel and Operational Managers to meet study timelines and funder requirements.
• Communicate laboratory performance, findings and technical issues through reports, presentations and discussions with study teams and collaborating laboratories, and contribute laboratory data and technical content to…