Clinical-Scientific - Bench Scientist

Job Overview

Job title:
Proteomics Bench Scientist

Location:

Andover, MA
Duration: 12 Months
Pay rate: $50-$57.14/hr.

Job Summary

Candidate will be responsible for developing proteomics workflows using advanced high-resolution mass spectrometry techniques. Key duties include development and optimization of sample preparation methods from cell lines and other matrices for mass spectrometry analysis and data processing with various bioinformatics tools; collaborative work with colleagues; accurately documenting all activities in an electronic lab notebook (ELN). This role requires expertise in LC-MS based proteomics.

Experience with cell culture and cell manipulation is a plus.

• Applying knowledge of proteomics workflows to develop and implement optimal strategies for the preparation and analysis of cellular samples
• Working collaboratively with experts in the team to advance innovative proteomics strategies
• Employing different bioinformatics tools for data analysis and fitting
• Consistent record keeping using an electronic lab notebook (ELN)

This hire will interact daily with the managers and 3-4 colleagues in the cross-functional team for method development, laboratory work prioritization, experiment planning and execution. The hire might also work on common assignments with colleagues in a larger bioanalytical group at the same location, as needed. The hire will participate in bi-weekly group meetings and other team meetings and discussions, as relevant to their work.

• M.S. with 5+ years, or Ph.D. with 0+ years in a relevant scientific field with documented experience in proteomics and mass-spectrometry

• Required:
  • Advanced knowledge and documented expertise with mass-spectrometry based proteomics approaches: label- or label-free quantification (TMT or DIA)
  • Experience with high-resolution mass-spectrometry instruments, such as Orbitraps and timsTOF
  • Experience with sample preparation based on enrichment (including affinity purification) and universal protein extraction
  • Bioinformatics skills relevant for mass-spec data search, statistical analysis and visualization
• Preferable:
  • Experience with membrane protein analysis and/or cell surface proteomics
  • Knowledge of cell culture techniques and experience conducting cell-based assays

• Walking, taking the stairs, standing, sitting as appropriate for a laboratory-based position

Work schedule: Monday - Friday / First shift flex

Interview: First round:
Teams Meeting;
Second round: onsite