Research Laboratory Tech Intermediate​/Associate

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

The Singer Lab in Pediatric Endocrinology seeks a Research Laboratory Technician to support studies of obesity and metabolic disease. The Technician performs routine animal and laboratory procedures under the scientific direction of the PI and designated project leads and coordinates schedules, resources, and coverage with the Lab Manager.

• Perform assigned mouse colony activities, including breeding, weaning, identification, genotyping, weighing, diet changes, maintaining diet-induced obesity cohorts, and record keeping; communicate updates and animal-health concerns promptly
• Perform approved mouse procedures, including glucose and insulin tolerance tests, euthanasia, tissue collection, and sample processing following training
• Perform laboratory methods including DNA/RNA isolation, cDNA preparation, PCR/qPCR, ELISA, help with flow cytometry staining, microscopy, and cell culture
• Perform testing and analysis of data from metabolic challenge tests, surveys, dietary recalls, and immune-marker studies resulting from clinical visits, using established methods under scientific direction
• Maintain complete experimental records, protocols, and sample inventories; collect and review data for quality and perform graphing and statistical analysis using methods specified by scientific project leads
• Prepare reagents, maintain clean work spaces, and assist with dishwashing, autoclaving, restocking, inventories, and other shared laboratory duties
• Communicate experimental progress and technical problems; contribute methods, figures, and data summaries for manuscripts and grants and support collaborative studies
• Coordinate experimental scheduling and technical backup with the Lab Manager and project leads; support student training within demonstrated proficiency and follow all research, safety, and animal-care requirements

• High school diploma or associate degree and 1 to 3 years of related experience working with laboratory mice in the research of obesity and metabolic disorders
• Experience with molecular and cellular laboratory techniques, including cell and tissue processing, tissue sectioning, DNA/RNA isolation, and microscopy
• Accurate record keeping, attention to detail, and ability to follow protocols, organize daily work, and communicate effectively
• Ability to work independently after training and collaboratively with a multidisciplinary research team
• An equivalent combination of education and experience may be accepted, including relevant undergraduate or graduate student research experience

• High school diploma or Associate's degree
• 1 year of experience

• Bachelor's degree in basic sciences or a related field
• Experience with mouse metabolic studies, tissue harvests, cell culture, PCR/qPCR, ELISA, flow cytometry, or imaging
• Experience handling human blood or other clinical samples, analyzing research data, or preparing and analyzing RNA-sequencing samples

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract,…