RiSM Internship: Pharmaceutical Formulation & Tech

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Pharmaceutical & Solid State Development is part of Pharma Technical Development and situated in Basel, Switzerland.

Our key expertise is the development of robust and economic processes for drug substances with tailor-made solid state properties and patient-centric formulations for the synthetic molecule portfolio of projects from early clinical studies to commercialization. We advance the design and delivery of transformative medicines by combining particle engineering, characterization, and formulation development - ensuring optimal drug performance, manufacturability, and patient-centric solutions from molecule to medicine.

• Review of the relevant literature applicable to the project
• Training in relevant SOPs and manufacturing/analytical equipment
• Manufacturing and characterization of spray dried amorphous solid dispersions
• Preparation and characterization of solid dosage forms
• Regular discussion of project progress with supervisors and planning of next steps
• Writing of final report

You are a University student (or you graduated within 12 months prior to the start date) preferably in the subject of Pharmaceutical Sciences, Pharmaceutical Technology or similar subjects and have an interest in formulation and manufacturing. Furthermore, you are interested in using and sharing your knowledge as part of your Internship in a modern working environment.

• Reliable and accurate working style in a non-GMP environment
• Team-oriented and decision-making personality
• Self-sufficient, problem solving-oriented work habits
• Good knowledge of MS-Office (Word, Excel, PowerPoint)
• Proficiency in English, German is a plus

This internship opportunity is one of a number of positions we offer in the department per semester and is suitable for writing a Master/Diploma thesis
.

The interviews will take place on an interview day with all considered candidates and representatives of the department.

• A Current CV and a Motivation Letter
• A certificate of enrollment (if you are currently studying)
• For Non-EU/EFTA citizens:
  Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies and you must be enrolled during the entire duration of the internship
• The RiSM task (see below)

The Final date to receive applications is 23.08.2026. All successful final candidates will be invited to a virtual interview day which will take place on 14.10.2026.

The Internship will start in October to December 2027 and has a duration of 9 to 12 months, please indicate your preferred start date in your application.

More information about the Roche Internship program in Synthetic Molecules (RiSM) and other opportunities within this program you can find here.

Are you ready to apply? We are looking for someone who thinks beyond the job offered - someone who knows that this position can be a rare springboard to many other opportunities.

Assume you are a formulation scientist that has the task to develop a poorly water soluble drug (MW 923.43 g/mol, LogP≈ 5.5 - 7.5. Solubility in DMSO: up to 100 mg/mL, Ethanol: up to ≈ 3-6 mg/mL) for the treatment of head-neck-cancer. What are your considerations with respect to the formulation, manufacturing technology and dosage form? Please use the information provided in the following article (Dana

E. Moseson, Trong Bien Tran, Bharathi Karunakaran, Rohan Ambardekar, Tze Ning Hiew, Trends in amorphous solid dispersion drug products approved by the U.S. Food and Drug Administration between 2012 and 2023, International Journal of Pharmaceutics: X, Volume 7, 2024, 100259, (Use the "Apply for this Job" box below).) to answer those questions. We anticipate receiving your answers in the form of a slide deck suitable for presentation to a project team (maximum of 5 slides, PDF format) alongside your application.

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