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RNA Biology Associate in oligonucleotide screening

Job in 4040, Basel, Kanton Basel-Landschaft, Switzerland
Listing for: Roche Holding AG
Full Time position
Listed on 2026-10-17
Job specializations:
  • Healthcare
    Medical Science, Clinical Research, Data Scientist
  • Research/Development
    Research Scientist, Medical Science, Clinical Research, Data Scientist
Salary/Wage Range or Industry Benchmark: 90000 - 120000 CHF Yearly CHF 90000.00 120000.00 YEAR
Job Description & How to Apply Below

Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft.

Werde Teil von Roche, wo jede Stimme zählt.

Die Position

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

Therapeutic Modalities (TMo) organization, accountable for translating disease biology into high-quality drug candidates across small molecules, large molecules, oligonucleotides, and genomic medicines. By integrating deep modality expertise with cross-disciplinary collaboration, TMo drives innovation within and across platforms to enable differentiated, sustainable therapeutic impact.

The opportunity

We are looking for an experienced Lab Associate with a focus on molecular biology and RNA biology tasks to join our Nucleic-acid-based medicines team. You will support screening oligonucleotide-based therapeutics and development of RNA technologies by setting up and executing various molecular biology assays.

  • Develop cell-based screening assays and perform cell culture maintenance
  • Implement lab automation for high throughput screening of oligonucleotides
  • Purification and handling of RNA samples
  • Perform digital PCR, quantitative PCR (qPCR) assays to support portfolio and platform projects
  • Prepare and process tissue samples from animal studies for subsequent molecular analyses.
  • Assist in setting up and executing advanced molecular biology assays, including transcriptome profiling (e.g., DRUG-Seq, BRB-Seq, RNA-Seq).
Who you are
  • B.Sc in molecular biology or related field with a minimum of 10 years experience in drug discovery or M.Sc with a minimum of 5 years experience
  • Experience with therapeutic oligonucleotides, including screening and in vitro characterization
  • Hands-on wet-lab experience with molecular biology, RNA biology techniques (qPCR) & lab automation, ideally in an industrial setup
  • Strong organizational skills and attention to detail
  • Ability to work collaboratively in a team environment

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Wer wir sind

Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.

Gemeinsam können wir eine gesündere Zukunft gestalten.

Roche ist ein Arbeitgeber, der die Chancengleichheit fördert.

Position Requirements
10+ Years work experience
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