Principal Statistical Methodology Data Scientist

The Position

The Statistical Methodology Data Scientists play a strategic role in enabling the adoption of fit-for-purpose statistical methodologies to drive scientific rigor and decision-making excellence. This team serves as a center of excellence focused on consultation, education, and outreach to ensure that innovative and appropriate methods are applied across programs and portfolios.

• You serve as a methodological thought partner to study teams, providing expert guidance on complex design and analysis across programs
• You lead the development and institutionalization of methodologies that improve decision-making at trial and portfolio levels (e.g., quantitative go/no-go criteria, simulation frameworks, model-based projections)
• You shape cross-functional understanding of innovative statistical methods through consultation, publications, and leadership of education efforts
• You anticipate regulatory trends and industry shifts, integrating relevant methodologies into internal practices and guiding external engagements
• You act as a connector across teams, surfacing recurring challenges and co-creating scalable solutions to elevate analytical excellence in the organization
• You drive external collaboration through active participation in consortia, joint working groups, or regulatory-facing initiatives
• You mentor junior staff and influence the strategic direction of Statistical Methodology through thought leadership, vision-setting, and capability building

• You hold a PhD (or equivalent experience) in Data Science, Statistics, Computer Science, or a related quantitative discipline
• You have 7+ years of experience designing and applying advanced analytics to complex biomedical data in clinical trial research
• You bring deep expertise in statistical computing and advanced modeling, with a track record of developing novel or custom analytical solutions
• You are recognized as a technical expert and thought partner within the organization or broader field
• You have experience mentoring others and contributing to internal standards, strategy, or capability development
• You show respect for cultural differences when interacting with colleagues in the global workplace

• Experience developing novel or fit-for-purpose analytical methods for different types of datasets
• Demonstrated leadership in designing scalable workflows or frameworks adopted across multiple projects or teams
• Track record of influencing portfolio- or program-level decisions through rigorous analytical insights
• Publications, presentations, or internal white papers that showcase innovative analytical thinking
• Thought leadership in emerging data science areas relevant to pharmaceutical development (e.g., AI/ML in translational research, real-world data integration, predictive biomarkers)

Roche is an Equal Opportunity Employer.