Senior Principal Scientist​/Associate Director Translational Oncology

Overview

This role is based in Basel, Switzerland. The Oncology Translational Research (OTR) group at Novartis Biomedical Research is seeking a highly accomplished translational scientist who combines exceptional scientific depth in cancer and molecular biology with the ability to lead, influence, and align complex, cross‑functional organizations.

This role is designed for a scientific leader who not only drives cutting‑edge research but also shapes broader program direction by connecting discovery, translational science, and clinical strategy. The successful candidate will play a pivotal role in advancing oncology programs by translating deep biological insights into impactful therapeutic and biomarker strategies, while effectively navigating and influencing a global, matrixed research environment.

• Define and drive translational research strategies grounded in deep expertise in cancer biology, molecular signaling, and biomarker science
• Translate complex biological insights into actionable therapeutic hypotheses and clinical development strategies
• Lead oncology programs from early discovery through clinical translation, ensuring scientific rigor and strategic alignment
• Oversee mechanism‑of‑action studies, combination strategies, and biomarker development
• Act as a key integrator across drug discovery, translational, bioinformatics, and clinical teams
• Influence decision‑making and align cross‑functional stakeholders within a global, matrixed organization
• Partner with computational and data science teams to integrate genomic, molecular, and translational datasets into program strategy
• Ensure robust interpretation of data into clear scientific and clinical insights
• Lead and mentor multidisciplinary teams, fostering a culture of scientific excellence, accountability, and collaboration
• Communicate scientific strategies and findings effectively to senior leadership, governance bodies, and external partners
• Contribute to external scientific visibility through publications, conferences, and collaborations

• PhD in Molecular Biology, Cancer Biology, Cell Biology, Biochemistry, Genetics, or a related scientific discipline
• Completed postdoctoral work plus at least 4+ years of biotechnology, pharmaceutical, or academic translational research experience (see leveling below)
• Demonstrated leadership experience in oncology research and translational therapeutic development
• Proven track record of leading multidisciplinary scientific programs in matrixed organizations
• Strong scientific communication, leadership, collaboration, and mentoring capabilities
• Established record of scientific innovation, publications, and translational impact
• High level of scientific curiosity, agility, and a positive, solution‑oriented mindset

At Novartis, we’re committed to reimagining medicine together — and rewarding the people who make it happen.

Salary
:
Expected Annual Base Salary Range for role: CHF 122,500 to CHF 227,500. The base salary offered is determined based on gender‑neutral objectives, such as relevant skills, competencies and experience in accordance with the Novartis pay setting policy and will be reviewed periodically upon joining Novartis.

In addition to your base salary, you may be eligible for a performance‑based bonus depending on certain performance parameters.

The rewards of being part of our team go far beyond base pay and incentives. We also offer a variety of competitive benefits in kind to help you thrive personally and professionally, such as insurance plans, retirement plans, wellbeing resources and global recognition programs. In addition, we provide flexible and hybrid working options, where possible, and a minimum of 14 weeks paid parental leave.

Pay equity is a fundamental principle of our employment policy and reflects our commitment to create a diverse, equitable and inclusive environment that treats all employees with dignity and respect, as outlined in our Code of Ethics.

Benefits and compensation may vary by country and are subject to local legal requirements, including provisions of collective bargaining agreements where applicable.

Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.