RiSM Internship for students in Pharmaceutical Sciences, Pharmaceutical Technology or Chemistry

Chez Roche, vous pouvez être vous-même et être apprécié pour les qualités uniques que vous apportez. Notre culture encourage l'expression personnelle, le dialogue ouvert et les connexions authentiques, où vous êtes valorisé, accepté et respecté pour ce que vous êtes, vous permettant de prospérer tant personnellement que professionnellement. Voici comment nous visons à prévenir, arrêter et guérir les maladies et à garantir à chacun l'accès aux soins de santé aujourd'hui et pour les générations à venir.

Rejoignez Roche, où chaque voix compte.

Pharmaceutical & Solid State Development is part of Pharma Technical Development and situated in Basel, Switzerland.

Our key expertise is the development of robust and economic processes for drug substances with tailor-made solid state properties and patient centric formulations for the synthetic molecule portfolio of projects from early clinical studies to commercialization. We advance the design and delivery of transformative medicines by combining particle engineering, characterization, and formulation development - ensuring optimal drug performance, manufacturability, and patient‑centric solutions from molecule to medicine.

As an intern you will support the department Pharmaceutical & Solid State Development in manufacturing and characterizing formulations of dispersible tablets at lab scale.

• Review of the relevant literature applicable to the project

• Training in relevant SOPs and manufacturing/analytical equipment

• Planning and conduction of formulation studies to select and optimize variants

• Characterization of formulations on manufacturability and disintegration performance

• Regular discussion of project progress with supervisors and planning of next steps

• Writing of final report

You are a University student (or you graduated within 12 months prior to the start date)
preferably in the subject of Pharmaceutical Sciences, Pharmaceutical Technology or Chemistry and have an interest in galenical and processing related questions. Furthermore, you are interested in using and sharing your knowledge as part of your Internship in a modern working environment. Your further profile for this position:

• Reliable and accurate working style in a non-GMP environment

• Team-oriented and decision‑making personality

• Self‑sufficient, problem solving‑oriented work habits

• Good knowledge of MS‑Office (Word, Excel, PowerPoint)

• Proficiency in English and German is a plus

This internship opportunity is one of a number of positions we offer in the department per semester and is not suitable for writing a Bachelor/Master/Diploma thesis.

The interviews will take place on an interview day with all considered candidates and representatives of the department.

For Non‑EU/EFTA citizens:
Due to regulations, you must provide a certificate issued by your university stating that an Internship is mandatory for your studies and you must be enrolled during the entire duration of the internship

Assume you are a formulation scientist that has the task to develop a poorly water soluble drug (MW 923.43 g/mol, LogP≈ 5.5 - 7.5. Solubility DMSO: up to 100 mg/mL, Ethanol: up to ≈ 3-6 mg/mL) for the treatment of head-neck-cancer. What are your considerations with respect to the formulation, manufacturing technology and dosage form? Please use the information provided in the following article (Dana

E. Moseson, Trong Bien Tran, Bharathi Karunakaran, Rohan Ambardekar, Tze Ning Hiew, Trends in amorphous solid dispersion drug products approved by the U.S. Food and Drug Administration between 2012 and 2023, International Journal of Pharmaceutics: X, Volume 7, 2024, 100259, (Use the "Apply for this Job" box below).) to answer those questions. We anticipate receiving your answers in the form of a slide deck suitable for presentation to a project team (maximum of 5 slides, PDF format) alongside your application.

Un avenir plus sain nous pousse à innover. Ensemble, plus de 100 000 employés à travers le monde sont dédiés à faire progresser la science et à garantir à chacun l'accès aux soins de santé aujourd'hui et pour les générations à venir. Nos efforts aboutissent à plus de 26 millions de personnes traitées avec nos médicaments et plus de 30 milliards de tests réalisés avec nos produits de Diagnostique.

Nous nous encourageons mutuellement à explorer de nouvelles possibilités, à favoriser la créativité et à conserver nos grandes ambitions, afin de fournir des solutions de santé qui changent des vies et ont un impact mondial.

Construisons ensemble un avenir plus sain.

Roche est un employeur offrant l'équité en matière d'emploi.