Research Associate, Computational Ion Channel Design, Synthetic and Structural Biology

The Institute of Molecular and Clinical Ophthalmology Basel (IOB) seeks a highly motivated Research Associate. IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded.

We are recruiting a Research Associate in computational ion channel and membrane-protein design (protein design, structural and synthetic biology). In this role, you will drive an end-to-end, design–build–test cycle:
computationally design engineered ion channels (e.g., light-responsive membrane proteins),
translate designs into expression constructs
, and validate function in mammalian systemsin collaboration with colleagues performing
quantitative assays (with access to high‑throughput electrophysiology and advanced imaging). The position combines modern structure‑based and generative design approaches with hands‑on experimental execution (mammalian cell culture, transfection/transduction, expression optimization, and protein/function characterization).