Project Leader in Cryo-Electron Tomography – Structural Biology Platform

Organisation/Company Friedrich Miescher Institute for Biomedical Research Research Field Biological sciences » Biology Biological sciences » Other Chemistry » Structural chemistry Physics » Biophysics Engineering » Other Researcher Profile Recognised Researcher (R2) Positions Research Support Positions Final date to receive applications 31 Mar 2026 - 23:59 (Europe/Zurich) Country Switzerland Type of Contract Permanent Job Status Full-time Hours Per Week 40 Offer Starting Date 16 Feb 2026 Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No

The Structural Biology Platform is hiring a Project Leader to advance cryo-electron tomography (cryo-ET) and expand its capabilities  platform supports an engaged research community working at the interface of structural biology, cell biology and molecular mechanisms of disease. The state-of-the-art cryo-EM facility includes an Aquilos2 with iFLM, a Titan Krios and a Glacios, offering an exceptional environment for cutting-edge structural studies.

• Support researchers with cryo-EM/ET sample preparation and data collection.
• Train users in the operation of transmission electron microscopes and cryo-FIB/SEM.
• Streamline data‑processing workflows for sub‑tomogram averaging and structure determination.
• Actively contribute to cryo-ET/EM projects development and publications.
• Provide technical documentation and ensure effective troubleshooting.

• PhD (or equivalent) in structural biology, natural sciences or related field.
• Hands‑on experience with cryo-ET/EM state‑of‑the‑art instrumentation.
• Proficiency in SPA, STA, and structure determination.
• Background in high‑pressure freezing and cryo‑lift‑out would be a plus.
• Excellent spoken and written English, IT skills, team player and proactive.

• A competitive compensation and benefit package.
• A 3‑year initial contract with the possibility of transitioning to a permanent position after 2 years.
• Opportunities to participate in conferences and courses to learn new techniques.
• A dynamic, multidisciplinary and international environment that values diversity, inclusion and the contributions of every individual.

Please submit your application online .ch/opening by March 31, 2026. Your application should include:

• A letter of motivation
• Your CV
• The names and contact details of 2–3 referees

The FMI is a world‑class biomedical research institute affiliated with the University of Basel and Novartis Biomedical Research. With an international staff of about 330 people, including more than 150 postdoctoral fellows and graduate students, the FMI conducts cutting‑edge research in genome regulation, multicellular systems and neurobiology. We are located in the vibrant city of Basel, Switzerland’s third‑largest city and Europe’s leading hub for the life sciences.

At the FMI, diversity is the cornerstone of innovation and collaboration. We foster an inclusive environment where everyone can thrive and contribute meaningfully. We welcome applicants of all genders, cultures, ethnicities, and demographics who can complement our existing team. Together, we aim to build a scientific community that reflects the diversity of the society we serve.