Research Associate, Cell Therapy Translational Research

Your position

• Hands-on development of a novel stem cell therapy for corneal regeneration
• Establish, optimize, and routinely perform stem cell culture, expansion, and characterization
• Directly execute ex vivo genome editing experiments in primary stem cells using base and prime editing
• Perform functional in vitro assays to assess stem cell identity, differentiation, and regenerative potential
• Generate and analyze single-cell RNA-seq and spatial transcriptomics data from primary tissues, cultured cells, and edited cells
• Independently design, perform, document, and interpret experiments in a reproducible manner
• Prepare and adapt laboratory protocols for technology transfer to a GMP facility
• Work closely with technical staff and assist in supervising research assistants, while remaining experimentally active
• Contribute experimentally to translational documentation, regulatory preparation, and clinical protocol development
• Develop and experimentally validate biomarkers for stem cell engraftment and function in human samples
• Present experimental results internally, to collaborators, and at international conferences
• Mentor junior lab members through direct experimental guidance and training

• PhD in Biology, Stem Cell Biology, Molecular Medicine, or a related field
• Strong hands-on experience with cell-based or stem cell therapies (e.g. epithelial stem cells, CAR T cells, iPSC-derived products)
• Demonstrated ability to work independently at the bench with primary human cells
• Practical experience with CRISPR-based genome engineering; experience with base or prime editing is highly desirable
• Solid background in cell culture, molecular biology, and in vitro functional assays
• Experience with single-cell RNA sequencing and/or spatial transcriptomics workflows
• Experience working under BSL-2 conditions
• Prior exposure to GMP environments or technology transfer is an advantage but not required
• Excellent organizational skills and strong attention to experimental detail
• Clear scientific communication skills and a collaborative working style