Research Associate Proteomics

Monte Rosa Therapeutics seeks to recruit a highly motivated research associate in proteomics with drug discovery experience to join its growing proteomics global team. This is an exciting opportunity to join a team responsible for the characterization of novel small molecule glue-based degraders to support Monte Rosa’s growing pipeline.

The successful candidate will be responsible for independently conducting own experiments from cell culture, sample preparation, LC-MS acquisition, to data analysis, interpretation, and presentation of the proteomics results. We are looking for a candidate with strong technical and organizational skills, and a strong collaborative spirit.

• Perform mass spectrometry/quantitative proteomics experiments with the use of nano LC-MS (Thermo Fisher) and proteomics bioinformatics software.
• Implement new innovative technologies/methodologies that may enhance proteomic workflows, in particular automation solutions for proteomics sample preparation workflows.
• Prepare biological samples for proteomics analysis and execute protein biochemical techniques (SDS page, Western blots, BCA, LC peptide fractionations).
• Work independently with minimal supervision to design, execute advanced experiments, analyze, interpret and communicate data in project team meetings.
• Be responsible for lab infrastructure, prepare and maintain laboratory reagents and stocks.

• BSc and/or MSc in analytical chemistry, biochemistry or related field.
• At least 1 year’s experience in protein mass spectrometry/proteomics in Pharma, Biotech or equivalent.
• Hands‑on experience with LC‑MS instrumentation (Thermo Fisher).
• Experience in culturing mammalian cells and sterile techniques is desirable.
• Experience in protein post‑translational modification analysis, protein‑protein‑interaction analysis, and targeted mass spectrometry analysis would be a plus.
• Critical and independent thinking with strong analytical and problem‑solving skills.
• Highly motivated, strong scientific curiosity and interest in drug discovery.
• Excellent oral and written communication skills to work in a collaborative, matrix team.