Bioengineer and 3D culture expert

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease.

We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research.

The Tumor Heterogeneity Metastasis and Resistance led by Prof. Mohamed Bentires‑Alj, is looking for a Bioengineer and 3D culture expert.

Join our community and help shape the future of biomedicine.

We are seeking a highly motivated and innovative Bioengineer specialized in complex 3D culture systems to join our multidisciplinary team at the interface of clinical research, biomedical imaging and personalized oncology. This position offers the opportunity to contribute directly to translational science and personalized cancer treatment decisions. You will be embedded in a dynamic, interdisciplinary team including clinicians, cancer biologists, organoid and drug screening experts, bioinformaticians, and data scientists.

We use state‑of‑the‑art technologies such as image‑based drug screening and imaging mass cytometry to inform clinical decision making for patients with advanced cancer.

• Drive the development of organ‑specific heterotypic 3D co‑culture models using patient‑derived tumor material, with iterative optimization of media compositions.
• Establish and scale miniaturized co‑culture platforms in 384‑well formats, enabling compatibility with automated high‑throughput drug screening workflows.
• Design and execute robust comparative drug screening assays to evaluate therapeutic responses.
• Develop and apply automation workflows, including liquid handling technologies, to ensure reproducible and high‑precision cell seeding.
• Work collaboratively with organoid specialists and data scientists in a highly interdisciplinary environment.
• Ensure rigorous documentation of experimental procedures and support the translation of methods toward clinically relevant, scalable high‑throughput applications.

• PhD degree or equivalent expertise in biomedical/tissue engineering, biology, biotechnology, or a related field.
• Hands‑on experience with complex 3D culture systems and their application in cancer research.
• Solid knowledge of cancer biology and tumor microenvironment dynamics.
• Practical expertise in imaging techniques and immunofluorescence.
• Strong organizational skills, pragmatic and clear mindset.
• Highly motivated, creative, team‑oriented, and collaborative.
• Excellent oral and written English communication skills.

Application:
Please upload your CV, a summary of your research experience and interests, techniques that you are competent in, and the contact details of three referees including your current PI at: (Use the "Apply for this Job" box below).-2026

Final date to receive applications:
Applications will be reviewed as they arrive.

Contact: thmrjobapplication-dbm