PhD Students in Vaccination-Induced B CELL Immunity Against LASSA VIRUS

Overview

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease. We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research.

The Experimental Virology, led by Prof. Daniel Pinschewer, is looking for two PhD students.

The successful applicants will investigate:

• how protective memory B cell immunity can be elicited by genetic vaccine technology, and
• how memory B cell immunity mediates protection against high-level viremia.

The project will exploit a broad range of cutting‑edge immunological and virological methods including innovative molecular vaccine design, B cell repertoire analyses (single‑cell cloning and next‑generation single‑cell sequencing) and somatic gene therapy‑based perturbation experiments in mice.

• We are looking for curious and hard‑working personalities with social skills, team spirit and a passion for research.
• Eagerness to learn, push your own limits and a strong desire to make fundamental discoveries are key attributes.
• Basic knowledge in immunology is required.
• Prior experience in immunological or virological research and/or in molecular biological approaches are a plus.