Vitro Bioanalysis Scientist

The Opportunity

Serving as a technical expert within the ADME chapter of Pharmaceutical Sciences (PS). The primary objective is to drive the discovery portfolio forward by providing high‑quality, actionable in vitro bioanalytical data that informs drug candidate selection.

• Mass Spectrometry & HPLC Operation: Independently develop and validate robust bioanalytical methods using HPLC and triple‑quad (Sciex) or high‑resolution (e.g. Orbitrap/Thermo) mass spectrometry.
• Multi‑Modality Quantification: Lead the quantification and rigorous data analysis for a diverse portfolio including small molecules, peptides, and oligonucleotides.
• Digital Transformation: Design and implement workflow automation and digitalization initiatives to streamline laboratory data flow and experimental execution.
• Strategic Throughput Optimization: Continuously evaluate and optimize the BA strategy to specifically increase sample throughput and reduce manual data analysis time.
• Large Molecule Support: Provide technical expertise for the quantification of large molecules as required by the pRED discovery pipeline; optimize BA strategy to increase throughput and automation of data analysis.
• Cross‑Functional
  
  Collaboration:
  
  Partner with the ADME team to interpret bioanalytical results and influence project progression.
• Roche Leadership Framework: Demonstrate a Creative Mindset and VACC (Visionary, Architect, Catalyst, Coach) principles in all interactions, even as an individual contributor.

An MSc or PhD degree in bioanalysis, biochemistry or a related relevant discipline, paired with proven practical experience, ideally within an industrial setting.

Take full ownership of the quality, accuracy, and timely delivery of in vitro bioanalytical data supporting discovery projects.

Exercise authority to permanently optimize laboratory processes, ensuring they meet evolving quality and efficiency standards.

Act as a primary technical point of contact for internal stakeholders, utilizing high‑level communication and collaboration skills to align on project needs.

Apply economic and entrepreneurial thinking to prioritize tasks and manage laboratory resources effectively within the ADME department.

Permanently optimizes processes in order to increase quality and efficiency standards.

Roche is an Equal Opportunity Employer. We believe it’s urgent to deliver medical solutions right now - even as we develop innovations for the future.