Senior Associate - Bioanalytical LC-MS Assay Developer

Senior Associate - Bioanalytical LC-MS Assay Developer

As a Senior Associate – Bioanalytical LC‑MS Assay Developer within our Bioanalytics and Biomarkers (BioAM) department, you will play a central role in shaping the non‑regulated preclinical and exploratory clinical pipeline. You will be responsible for developing, qualifying, and validating advanced bioanalytical methods to quantify drug candidates and biomarkers across diverse chemical classes—from small molecules and oligonucleotides to complex proteins. In this role, you combine hands‑on laboratory expertise with modern digital tools to transform biological samples into high‑quality data that directly impacts project decisions.

• Develop, qualify, and validate analytical methods for the accurate quantification of drug candidates, metabolites, and biomarkers in various biological matrices.
• Apply bioanalytical and biomarker assays to support non‑clinical pharmacokinetic (PK) and toxicokinetic (TK) studies and exploratory clinical studies following Good Clinical Practice (GCP) principles where required.
• Ensure accurate documentation of experimental data and contribute to comprehensive technical reporting, including Bioanalytical Reports and Analytical Method Descriptions.
• Take ownership of laboratory equipment care, maintenance, and the management of consumable stocks within your assigned workspace to guarantee operational excellence.
• Maintain, refine, and proactively advance your technical expertise in Liquid Chromatography–Mass Spectrometry (LC‑MS/MS) and automated sample preparation.
• Leverage IT and digital tools for efficient experimental design, data analysis, and documentation, presenting scientific results confidently to cross‑functional project teams.

• A Master’s or Bachelor’s degree in Analytical Chemistry, Biochemistry, or a related field, supplemented by relevant professional experience.
• Solid hands‑on experience and training in modern analytical techniques, specifically focusing on quantitative liquid chromatography combined with mass spectrometric detection (LC‑MS/MS).
• Proficient track record utilizing computerized data acquisition systems, analytical processing software, and automated sample preparation techniques.
• Demonstrated capability or strong open mindset toward utilizing IT and digital/AI‑supported workflows for experimental design, data tracking, and data presentation.
• Excellent team spirit with a dedicated focus on delivery, open communication, and collaboration with cross‑functional partner departments to meet project timelines.

Roche is an Equal Opportunity Employer.