Vitro Bioanalysis Scientist

Position

We are looking for a technical expert within the ADME chapter of Pharmaceutical Sciences (PS). The primary objective is to drive the discovery portfolio forward by providing high-quality, actionable in vitro bioanalytical data that informs drug candidate selection.

• Mass Spectrometry & HPLC Operation:
  Independently develop and validate robust bioanalytical methods using HPLC and triple quad (Sciex) or high‑resolution (e.g., Orbitrap/Thermo) mass spectrometry.
• Multi‑Modality Quantification:
  Lead the quantification and rigorous data analysis for a diverse portfolio including small molecules, peptides, and oligonucleotides.
• Digital Transformation:
  Design and implement workflow automation and digitalisation initiatives to streamline laboratory data flow and experimental execution.
• Strategic Throughput Optimization:
  Continuously evaluate and optimise the BA strategy to increase sample throughput and reduce manual data analysis time.
• Large Molecule Support:
  Provide technical expertise for the quantification of large molecules as required by the pRED discovery pipeline.
• Cross‑Functional
  
  Collaboration:
  
  Partner with the ADME team to interpret bioanalytical results and influence project progression.
• Apply Roche Leadership Framework:
  Demonstrate a Creative Mindset and VACC (Visionary, Architect, Catalyst, Coach) principles in all interactions.

• MSc or PhD in bioanalysis, biochemistry or a related discipline, with practical experience in an industrial setting.
• Ownership of the quality, accuracy and timely delivery of in‑vitro bioanalytical data supporting discovery projects.
• Ability to permanently optimise laboratory processes and ensure they meet evolving quality and efficiency standards.
• Effective communication and collaboration skills to act as primary technical point of contact for internal stakeholders.
• Enterprise and entrepreneurial thinking to prioritise tasks and manage laboratory resources effectively within the ADME department.

Roche is an Equal Opportunity Employer.