Student Internship in Analytical Development Peptide Characterization LC-MS

At Roche, we offer an internship in the Synthetic Molecule Analytical Development department (PTDC-A) within Global Technical Development (PTD). You will work with a team of more than 20 mass spectrometry experts to develop and validate modern LC‑MS/MS methods that support the safety and efficacy of synthetic molecule development products.

• Develop a modern LC‑MS/MS method for determining the enantiomeric purity (D/L ratio) of amino acids in synthetic peptides.
• Prepare samples, including peptide hydrolysis, and conduct precise LC‑MS/MS measurements.
• Interpret complex analytical mass spectrometry data and contribute to method validation.
• Collaborate with senior Roche scientists and cross‑functional teams to ensure methods meet quality and regulatory standards.
• Assist in bridging the gap between academic theory and industrial application within the drug development lifecycle.

• Recent Master’s graduate or student nearing completion of a Master’s degree in analytical chemistry, chemistry, biochemistry, pharmacy, or a related field.
• Solid theoretical foundation and practical experience with analytical instrumentation, chromatographic separation techniques, and sample preparation.
• Curious, proactive, and hands‑on mindset with strong problem‑solving skills.
• Business proficiency in English;
  German knowledge is a plus.
• Experience with LC‑MS analytics and familiarity with derivatization techniques or acid hydrolysis is an advantage.
• Ability to work independently while being a committed team player.

Start date:

upon agreement with the line manager. Applicants should submit a current CV and a motivation letter. EU/EFTA/Swiss citizens must provide proof of current enrollment or a Master’s degree obtained within the last 12 months. Non‑EU/EFTA citizens must provide proof of current enrollment and certify that the internship is mandatory for their studies. Please indicate in your application if the internship will be used for thesis writing.

Roche is an Equal Opportunity Employer. We believe in delivering medical solutions to everyone, and we value diversity, integrity, and innovation in all our activities.