Research Associate in-vivo Pharmacology in Cardiovascular and Metabolic Diseases - Temporary Po

Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst. Gemeinsam wollen wir Krankheiten vorbeugen, stoppen und heilen und sicherstellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und in Zukunft.

Werde Teil von Roche, wo jede Stimme zählt.

In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

pRED Cardiovascular & Metabolism, Immunology (CMI), located in Basel, Switzerland, focuses on the discovery and early development of innovative treatments for specific diseases that affect the lives of millions. In the cardiovascular and metabolism area, we are developing cutting-edge therapies to treat metabolic diseases.

We are currently looking for a diligent and highly motivated Research Associate with a strong industry background to join our Cardiovascular and Metabolic Diseases (CVM) in-vivo pharmacology department. In this role, you will design and execute in-vivo experiments in rodents to evaluate the pharmacodynamics, efficacy and safety of novel therapeutic candidates for cardiovascular and metabolic diseases.

• Establish, validate and use disease relevant rodent models (e.g., obesity and diabetes) and readouts to support various drug discovery projects.

• Collaboratively design and execute in-vivo studies, and interpret data from in-vivo experiments to assess the pharmacodynamics and therapeutic efficacy of novel compounds.

• Support the development and characterization of novel in-vivo models for obesity-related comorbidities.

• Diligently follow national and international animal welfare laws, and align with the company's commitment to the 3
  
  Rs (Replace, Reduce, Refine).

• Continuously improve test systems, analyses, and data evaluation. Contribute to work process optimization including data capture, storage and assay automation.

• Work closely with all members of the group, share duties, maintain a clean work environment and actively contribute to the positive work atmosphere within the group.

• MSc/BSc in Life Sciences or completion of an apprenticeship for a research associate (“Lehrabschluss”)(no PhD) with at least 3 years of industry experience working with in-vivo models.

• Mouse work experience required; managing animal cohorts, injections via various routes, behavioral assays, mouse monitoring, tissue sampling and processing.

• LTK1 or equivalent is required.

• Experience in rodent models of obesity and functional readouts, such as glucose and insulin tolerance tests, body composition analysis, whole-body metabolism (Promethion), blood pressure.

• You communicate effectively in English, both in writing and orally. Skillfully able to interact with people and have strong commitment to teamwork.

• Excellent data management and record-keeping skills are required.

At Roche, we aim high to deliver life-changing healthcare solutions. If you’re ready to make a meaningful impact on patients and healthcare systems worldwide, this is the place for you.

Eine gesündere Zukunft treibt uns zur Innovation an. Mehr als 100.000 Mitarbeiter weltweit arbeiten gemeinsam daran, wissenschaftliche Fortschritte zu erzielen und sicherzustellen, dass jeder Zugang zur Gesundheitsversorgung hat – heute und für zukünftige Generationen. Durch unser Engagement werden über 26 Millionen Menschen mit unseren Medikamenten behandelt und mehr als 30 Milliarden Tests mit unseren Diagnostik-Produkten durchgeführt. Wir ermutigen uns gegenseitig, neue Möglichkeiten zu erkunden, Kreativität zu fördern und hohe Ziele zu setzen, um lebensverändernde Gesundheitslösungen zu liefern.

Gemeinsam können wir eine gesündere Zukunft gestalten.

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