Research​/Lab Assistant; in Vivo Systems Neuroscience and Neurodegeneration

As a joint venture of the University of Basel and the University Hospitals Basel, the Department of Biomedicine (DBM) brings together basic and clinical scientists to advance the understanding of health and disease.

We are home to more than 67 research groups and over 800 employees across six locations in the heart of Basel. Our collaborative and international environment fosters innovation, excellence, and impactful research.

The Brain Ageing and Neurodegenerationled by Prof. Marc Aurel Busche, is looking for a Research / Lab Assistant.

Join our community and help shape the future of biomedicine.

We are looking for a motivated and technically skilled Research / Lab Assistant (80%) to join a newly funded project investigating how tau pathology disrupts neural circuit function during the early stages of Alzheimer's disease.

The project combines mouse behaviour, chronic multi-region electrophysiological recordings (Neuropixels), viral approaches, and analysis of large-scale neural population activity to study how pathological changes in neural activity emerge and contribute to cognitive impairment.

• Perform and support experimental procedures in mice, including stereotaxic surgeries, behavioural training and testing and chronic in vivo electrophysiological recordings
• Support histological processing and sample preparation for ex vivo experiments
• Support the monitoring of animals before, during, and after experimental procedures

• Valid certification to perform animal experiments in Switzerland (LTK1 or equivalent qualification)
• At least 1 year of hands-on experience with in vivo experiments in rodents, gained through a technical apprenticeship, veterinary technician training, or a Bachelor's/Master's degree in a relevant field
• Experience working with rodents in a research environment, including animal handling, welfare monitoring, and experimental documentation
• Experience with stereotaxic surgery in rodents
• Good communication skills in English

Preferred

• Experience with in vivo electrophysiology and/or neural recording techniques
• Experience with behavioural neuroscience experiments
• Ability to communicate in German is an advantage

• A 2-year fixed-term position (80%)
• Training in advanced in vivo neuroscience techniques, including chronic Neuropixels recordings
• Opportunity to contribute to establishing new experimental workflows and longitudinal studies
• An international and collaborative research environment

www.unibas.ch