Lead Chemical Process R&D Scientist

For our client, a globally leading company in the life sciences and pharmaceutical industry headquartered in Basel, we are currently looking for a Senior Chemical Process R&D Lead (m/f/d).

In this exciting role, you will lead chemical process research and development activities, focusing on the optimization and scale‑up of chemical manufacturing processes for pharmaceutical active ingredients and intermediates, particularly in late‑stage development. Working closely with internal teams and external development and manufacturing partners, you will ensure the delivery of safe, efficient, high‑quality, and sustainable chemical processes.

• Start date: ASAP or by agreement, latest possible start date: 1 February 2027
• Duration: 1 year, with a likely extension option
• Home office: Up to 2 days per week

• Lead internal and external chemical process research and development activities.
• Provide technical leadership to an internal team of 1–5 process chemists and coordinate activities at external contract development and manufacturing organizations (CDMOs).
• Oversee the development, optimization, and scale‑up of chemical synthesis processes, from route scouting to larger‑scale manufacturing.
• Coordinate internal laboratory activities and external manufacturing partners to ensure the timely supply of active pharmaceutical ingredients (APIs) and intermediates.
• Plan and oversee technology transfers as well as external development and manufacturing activities.
• Ensure compliance with quality requirements, product specifications, safety standards, and sustainability objectives.
• Collaborate closely with internal and external stakeholders to ensure efficient project execution and reliable project delivery.

• PhD or postdoctoral background in synthetic organic chemistry.
• At least 5 years of professional experience in pharmaceutical chemical process R&D.
• Strong expertise in process optimization and scale‑up, particularly in late‑stage development.
• Proven experience in leading teams and managing development projects.
• Hands‑on experience managing external development and manufacturing partners (CDMOs), including technology transfers.
• Proficiency in standard office applications and chemistry‑related tools, including chemical drawing software, literature and patent search platforms, Design of Experiments (DoE) applications, and project planning tools.
• Experience in GMP‑regulated environments is an advantage.
• Knowledge of kinetic modelling or scale‑up simulation software is a plus.
• Professional fluency in written and spoken English;
  German language skills are an advantage.
• Strong analytical, organizational, and problem‑solving skills, combined with a structured and results‑oriented approach.
• Excellent communication and collaboration skills, with the ability to lead, motivate, and align internal teams and external partners towards shared project goals.