Experienced Discovery Scientist in Immunology

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In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility, and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.

In the Immunology Department of pRED’s Cardiovascular, Metabolism, Immunology, Infectious Diseases (CMI2), we focus on the discovery and early development of innovative treatments for inflammatory diseases that affect the lives of millions.

To complement the Immunology team in pRED CMI2, we are seeking a visionary, strategic, experienced Discovery Scientist with a strong academic background in inflammation research, a track record in drug discovery from target discovery to Ph1 and proven ability to effectively lead teams and projects.

As an experienced Discovery Scientist in pRED CMI2, you will be a core scientific leader of an international and multidisciplinary group of scientists and clinicians committed to delivering innovative solutions for patients living with IBD, COPD and other inflammatory diseases by combining cutting-edge approaches in biology, pharmacology and translational research.

Key Responsibilities:

• Scientific leadership and strategy: define and execute the scientific strategy for novel target identification and validation in inflammatory diseases
• Project leadership: lead cross-functional teams to drive pipeline programs from early discovery to IND-enabling stages.
• Subject matter leadership: with our dedicated team of lab-based associates and post-doctoral scientists, you will direct, oversee and interpret complex preclinical experimental studies for the validation and characterisation of targets or therapeutic approaches.

• External representation and partnerships:
  As an internal expert in evaluating external licensing opportunities and academic collaborations, you will be a member of diligence teams and present the findings to leadership
• Mentorship and development:
  Managing, mentoring and developing scientists and postdocs to foster a culture of collaboration, innovation, and scientific rigor.

• You hold a PhD degree in Life Sciences (cellular/ molecular biology, pharmacology, immunology - or closely related field) and bring >10 years of experience in the pharmaceutical industry.
• You bring deep expertise in disease biology of inflammatory diseases, including inflammatory bowel disease and/or chronic obstructive pulmonary disease
• You have led drug discovery projects in the pharmaceutical / biotech industry and collaborated on in- or out-licensing activities. You have a good understanding of pharmacological properties of therapeutic modalities such as small molecules and antibodies.
• You have significant scientific accomplishments and successful collaborations documented by publications in high-impact journals
• You value collaboration within and across teams and have a strong visionary and strategic thinking capacity. You integrate clinical and…