Director, Procurement CMC Outsourcing

Why Sarepta? Why Now?

The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold a leadership position in Duchenne muscular dystrophy (Duchenne) and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.

We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.

At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work‑life resources designed to support people in the following areas:

• Physical and Emotional Wellness
• Financial Wellness
• Support for Caregivers

For a full list of our comprehensive benefits, see our website:

The Director, Procurement CMC Outsourcing builds, operationalizes, and executes strategic sourcing strategies for CDMO/CMO and Testing Labs to support our Manufacturing, Quality, Process Development, and Supply Chain organization. This role also integrates supplier selection, negotiation and contracting, and supplier relationship management with consolidation of spend in partnership across Supply Strategy & Planning, Quality Assurance, Quality Control, Process Development Global Manufacturing and Global Supply Chain.

The role interfaces closely with business partners to understand business priorities and needs, and in turn, defines specific initiatives to support Sarepta business priorities and growth.

• Collaborates and builds productive relationships with Supply Chain, Quality, Process Development and Manufacturing business partners and stakeholders while developing relationships with external key suppliers/ CDMO/CMO to identify opportunities to gain efficiencies, drive cost savings, proactively respond to business needs, and reduce risk while fulfilling business requirements.
• Partnering with stakeholders to align prioritization and lead execution.

• Support the development category and sourcing strategies for siRNA program development and clinical material supply, and commercial launch readiness. Identify potential CDMO/CMO for new programs and ensure right‑size capacity for programs/products at different stages.
• Lead category strategy implementation as well as value creation initiatives in support of business priorities and deliver cost savings in Drug Substance, Drug Product, Pack & Label, and domestic and internal Distribution.
• Support the business team with identification of all applicable risks as part of the Sourcing process, including coordination with the key business stakeholder to properly assess and develop mitigation plans, where necessary.
• Ensure accurate reporting of Procurement key performance measures (operational metrics, savings, quality, customer service, etc.) for the category and track ROI.
• Identify COGS savings opportunities and drive implementation.

• Lead supplier identification / selection and implement RFx activities.
• Lead negotiations of clinical and commercial supply agreements with key suppliers/CMOs/CMP Labs, and drive prioritization alignment across Business, Finance and Legal and external partners.
• Implement RFx activities.
• Prepare and implement advanced negotiation strategies. Manage complex negotiations on price and terms, partnering with stakeholders and Legal to negotiate and finalize agreements.

• Manage the Supplier/CMO Performance/Relationship Management process and ensure performance and accountability are tracked and improved.
• Maximize values from our supplier relationships.
• Develop and maintain strong vendor relationships to ensure continuity of supply and innovation in processes.

• 10+ years of demonstrated…